Severe Acute Respiratory Syndrome Coronavirus 2 Evolution and Escape From Combination Monoclonal Antibody Treatment in a Person With HIV

• Published in: Open forum infectious diseases Vol. 10; no. 2; p. ofad054
• Main Authors: Khosravi, Dara, Soloff, Hannah, Langsjoen, Rose M, Bombin, Andrei, Kelley, Colleen F, Ray, Susan M, Gunthel, Clifford J, Zanoni, Brian C, Nguyen, Phuong-Vi, Waggoner, Jesse J, Wang, Yun F, Cantos, Valeria D, Piantadosi, Anne
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 01.02.2023
• Subjects: Brief Report; SARS-CoV-2; immunocompromised; HIV; monoclonal antibody; virus evolution

Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) escape from combination monoclonal antibody treatment is rarely reported. We describe an immunocompromised individual with human immunodeficiency virus and persistent SARS-CoV-2 infection in whom substantial SARS-CoV-2 evolution o...