Development of Strong and Tough β-TCP/PCL Composite Scaffolds with Interconnected Porosity by Digital Light Processing and Partial Infiltration

Strong and tough β-TCP/PCL composite scaffolds with interconnected porosity were developed by combining digital light processing and vacuum infiltration. The composite scaffolds were comprised of pure β-TCP, β-TCP matrix composite and PCL matrix composite. The porous β-TCP/PCL composite scaffolds sh...

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Published inMaterials Vol. 16; no. 3; p. 947
Main Authors Wu, Yanlong, Chen, Ruomeng, Chen, Xu, Yang, Yongqiang, Qiao, Jian, Liu, Yaxiong
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 19.01.2023
MDPI
Subjects
Biological activity
Biomedical materials
Bones
Comparative analysis
digital light processing
Fatigue
Fatigue life
Fatigue strength
Fatigue testing machines
Flexural strength
Fractures
gradient structure
Infiltration
Materials
Mechanical properties
Polymers
Porosity
porous composite scaffolds
Porous media
Raw materials
Rubber
Scaffolds
Silicones
Strain energy
Substitute bone
Transmission Control Protocol/Internet Protocol (Computer network protocol)
Weibull modulus
China
digital light processing
infiltration
mechanical properties
porous composite scaffolds
gradient structure
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Summary:Strong and tough β-TCP/PCL composite scaffolds with interconnected porosity were developed by combining digital light processing and vacuum infiltration. The composite scaffolds were comprised of pure β-TCP, β-TCP matrix composite and PCL matrix composite. The porous β-TCP/PCL composite scaffolds showed remarkable mechanical advantages compared with ceramic scaffolds with the same macroscopic pore structure (dense scaffolds). The composite scaffolds exhibited a significant increase in strain energy density and fracture energy density, though with similar compressive and flexural strengths. Moreover, the composite scaffolds had a much higher Weibull modulus and longer fatigue life than the dense scaffolds. It was revealed that the composite scaffolds with interconnected porosity possess comprehensive mechanical properties (high strength, excellent toughness, significant reliability and fatigue resistance), which suggests that they could replace the pure ceramic scaffolds for degradable bone substitutes, especially in complex stress environments.
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These authors contributed equally to this work.
ISSN:1996-1944
1996-1944
DOI:10.3390/ma16030947