Acinetobacter baumannii as an oro-dental pathogen: a red alert

• Published in: Journal of applied oral science Vol. 32; p. e20230382
• Main Author: Girija, A S Smiline
• Format: Journal Article
• Language: English; Portuguese
• Published: Brazil Faculdade De Odontologia De Bauru - USP 01.01.2024; University of São Paulo
• Subjects: Acinetobacter baumannii; Acinetobacter baumannii - pathogenicity; Acinetobacter Infections - microbiology; Biofilm; Biofilms; DENTISTRY, ORAL SURGERY & MEDICINE; Drug Resistance, Bacterial; Humans; Mouth - microbiology; Mouth Diseases - microbiology; Mouth Neoplasms - microbiology; Oral cancer; Oral health; Review; Virulence; Virulence Factors - analysis; Biofilm; Acinetobacter baumannii; Oral cancer; Virulence; Oral health
• ISSN: 1678-7757; 1678-7765; 1678-7765
• DOI: 10.1590/1678-7757-2023-0382

This review highlights the existence and association of Acinetobacter baumannii with the oro-dental diseases, transforming this systemic pathogen into an oral pathogen. The review also hypothesizes possible reasons for the categorization of this pathogen as code blue due to its stealthy entry into the oral cavity. Study data were retrieved from various search engines reporting specifically on the association of A. baumannii in dental diseases and tray set-ups. Articles were also examined regarding obtained outcomes on A. baumannii biofilm formation, iron acquisitions, magnitude of antimicrobial resistance, and its role in the oral cancers. A. baumannii is associated with the oro-dental diseases and various virulence factors attribute for the establishment and progression of oro-mucosal infections. Its presence in the oral cavity is frequent in oral microbiomes, conditions of impaired host immunity, age related illnesses, and hospitalized individuals. Many sources also contribute for its prevalence in the dental health care environment and the presence of drug resistant traits is also observed. Its association with oral cancers and oral squamous cell carcinoma is also evident. The review calls for awareness on the emergence of A. baumannii in dental clinics and for the need for educational programs to monitor and control the sudden outbreaks of such virulent and resistant traits in the dental health care settings.