Robotic assessment of neuromuscular characteristics using musculoskeletal models: A pilot study

• Published in: Computers in biology and medicine Vol. 86; pp. 82 - 89
• Main Authors: Jayaneththi, V.R, Viloria, J, Wiedemann, L.G, Jarrett, C, McDaid, A.J
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 01.07.2017; Elsevier Limited
• Subjects: Accuracy; Activation; Activation analysis; Adult; Biomechanical Phenomena; Cerebral palsy; Effectiveness; Electrodes; Electromyography; Electromyography (EMG); Errors; Exoskeleton Device; Feasibility; Feasibility studies; HD-sEMG; Humans; In vivo methods and tests; Injuries; Internal Medicine; Kinematics; Kinetics; Male; Models, Biological; Muscle Strength; Muscle, Skeletal - physiopathology; Musculoskeletal modeling; Musculoskeletal system; Neuromuscular characterization; Open source software; Optimization; Other; Physiology; Pilot Projects; Rehabilitation; Rehabilitation - instrumentation; Rehabilitation - methods; Rehabilitation robots; Reproducibility; Robotic rehabilitation; Robotics; Robots; Stiffness; Variability; Viscoelasticity; Viscosity; Robotic rehabilitation; Musculoskeletal modeling; Neuromuscular characterization; Electromyography (EMG); HD-sEMG
• ISSN: 0010-4825; 1879-0534
• DOI: 10.1016/j.compbiomed.2017.05.007

Abstract Objective Non-invasive neuromuscular characterization aims to provide greater insight into the effectiveness of existing and emerging rehabilitation therapies by quantifying neuromuscular characteristics relating to force production, muscle viscoelasticity and voluntary neural activation. In this paper, we propose a novel approach to evaluate neuromuscular characteristics, such as muscle fiber stiffness and viscosity, by combining robotic and HD-sEMG measurements with computational musculoskeletal modeling. This pilot study investigates the efficacy of this approach on a healthy population and provides new insight on potential limitations of conventional musculoskeletal models for this application. Methods Subject-specific neuromuscular characteristics of the biceps and triceps brachii were evaluated using robot-measured kinetics, kinematics and EMG activity as inputs to a musculoskeletal model. Results Repeatability experiments in five participants revealed large variability within each subjects evaluated characteristics, with almost all experiencing variation greater than 50% of full scale when repeating the same task. Conclusion The use of robotics and HD-sEMG, in conjunction with musculoskeletal modeling, to quantify neuromuscular characteristics has been explored. Despite the ability to predict joint kinematics with relatively high accuracy, parameter characterization was inconsistent i.e. many parameter combinations gave rise to minimal kinematic error. Significance: The proposed technique is a novel approach for in vivo neuromuscular characterization and is a step towards the realization of objective in-home robot-assisted rehabilitation. Importantly, the results have confirmed the technical (robot and HD-sEMG) feasibility while highlighting the need to develop new musculoskeletal models and optimization techniques capable of achieving consistent results across a range of dynamic tasks.