Preoperative platelet distribution width predicts bone metastasis in patients with breast cancer

Bone metastases occur in 50-70% of patients with breast cancer (BC) and result in high mortality. Platelet distribution width (PDW), a commonly used parameter of activated platelets, has been associated with a poor prognosis in BC. We aim to investigate the prognostic role of PDW for bone metastasis...

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Published inBMC cancer Vol. 24; no. 1; pp. 1066 - 7
Main Authors Song, Mei-Yue, Zhao, Lin, Huang, Wen-Juan, Cui, Ming-Ming, Liu, Yu-Xi, Wang, Rui-Tao, Zhang, Xin
Format Journal Article
LanguageEnglish
Published England BioMed Central Ltd 29.08.2024
BioMed Central
BMC
Subjects
Adult
Aged
Analysis
Blood platelets
Blood Platelets - pathology
Bone cancer
Bone metastasis
Bone Neoplasms - blood
Bone Neoplasms - secondary
Bone surgery
Breast cancer
Breast Neoplasms - blood
Breast Neoplasms - pathology
Cancer
Cancer patients
Cancer therapies
Care and treatment
Development and progression
Diagnosis
Disease susceptibility
Endothelium
Female
Females
Growth factors
Health aspects
Hemoglobin
Hospitals
Humans
Kaplan-Meier Estimate
Lymph nodes
Lymphatic system
Measurement
Medical colleges
Medical prognosis
Metastases
Metastasis
Middle Aged
Multivariate analysis
Oncology, Experimental
Ovarian cancer
Patients
Platelet Count
Platelet distribution width
Platelets
Preoperative Period
Prognosis
Retrospective Studies
Risk Factors
Surgery
Tomography
China
Canada
United Kingdom
Bone metastasis
Breast cancer
Platelet distribution width
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Abstract Bone metastases occur in 50-70% of patients with breast cancer (BC) and result in high mortality. Platelet distribution width (PDW), a commonly used parameter of activated platelets, has been associated with a poor prognosis in BC. We aim to investigate the prognostic role of PDW for bone metastasis in BC patients. 515 patients who received BC surgery in the Harbin Medical University Cancer Hospital from July 1, 2016, to December 31, 2017, were reviewed. Patients' characteristics and platelet indices upon enrollment in this study were collected. The Kaplan-Meier method was used to estimate the 5-year bone metastasis incidence. The univariate and multivariate Cox regression analyses were utilized to identify risk factors associated with bone metastasis. The patients with bone metastases exhibited lower PDW levels than the patients without bone metastases. Moreover, decreased PDW was significantly correlated with histologic type, multifocal disease, and lymph node status. In addition, the patients with reduced PDW levels were more likely to develop bone metastasis. Multivariate analysis showed that PDW was an independent predictor for bone metastasis. PDW is an independent predictor of bone metastasis in BC. Further research is warranted.
AbstractList Abstract Purpose Bone metastases occur in 50-70% of patients with breast cancer (BC) and result in high mortality. Platelet distribution width (PDW), a commonly used parameter of activated platelets, has been associated with a poor prognosis in BC. We aim to investigate the prognostic role of PDW for bone metastasis in BC patients. Methods 515 patients who received BC surgery in the Harbin Medical University Cancer Hospital from July 1, 2016, to December 31, 2017, were reviewed. Patients’ characteristics and platelet indices upon enrollment in this study were collected. The Kaplan-Meier method was used to estimate the 5-year bone metastasis incidence. The univariate and multivariate Cox regression analyses were utilized to identify risk factors associated with bone metastasis. Results The patients with bone metastases exhibited lower PDW levels than the patients without bone metastases. Moreover, decreased PDW was significantly correlated with histologic type, multifocal disease, and lymph node status. In addition, the patients with reduced PDW levels were more likely to develop bone metastasis. Multivariate analysis showed that PDW was an independent predictor for bone metastasis. Conclusion PDW is an independent predictor of bone metastasis in BC. Further research is warranted.
PurposeBone metastases occur in 50-70% of patients with breast cancer (BC) and result in high mortality. Platelet distribution width (PDW), a commonly used parameter of activated platelets, has been associated with a poor prognosis in BC. We aim to investigate the prognostic role of PDW for bone metastasis in BC patients.Methods515 patients who received BC surgery in the Harbin Medical University Cancer Hospital from July 1, 2016, to December 31, 2017, were reviewed. Patients’ characteristics and platelet indices upon enrollment in this study were collected. The Kaplan-Meier method was used to estimate the 5-year bone metastasis incidence. The univariate and multivariate Cox regression analyses were utilized to identify risk factors associated with bone metastasis.ResultsThe patients with bone metastases exhibited lower PDW levels than the patients without bone metastases. Moreover, decreased PDW was significantly correlated with histologic type, multifocal disease, and lymph node status. In addition, the patients with reduced PDW levels were more likely to develop bone metastasis. Multivariate analysis showed that PDW was an independent predictor for bone metastasis.ConclusionPDW is an independent predictor of bone metastasis in BC. Further research is warranted.
Purpose Bone metastases occur in 50-70% of patients with breast cancer (BC) and result in high mortality. Platelet distribution width (PDW), a commonly used parameter of activated platelets, has been associated with a poor prognosis in BC. We aim to investigate the prognostic role of PDW for bone metastasis in BC patients. Methods 515 patients who received BC surgery in the Harbin Medical University Cancer Hospital from July 1, 2016, to December 31, 2017, were reviewed. Patients' characteristics and platelet indices upon enrollment in this study were collected. The Kaplan-Meier method was used to estimate the 5-year bone metastasis incidence. The univariate and multivariate Cox regression analyses were utilized to identify risk factors associated with bone metastasis. Results The patients with bone metastases exhibited lower PDW levels than the patients without bone metastases. Moreover, decreased PDW was significantly correlated with histologic type, multifocal disease, and lymph node status. In addition, the patients with reduced PDW levels were more likely to develop bone metastasis. Multivariate analysis showed that PDW was an independent predictor for bone metastasis. Conclusion PDW is an independent predictor of bone metastasis in BC. Further research is warranted. Keywords: Breast cancer, Bone metastasis, Platelet distribution width
Bone metastases occur in 50-70% of patients with breast cancer (BC) and result in high mortality. Platelet distribution width (PDW), a commonly used parameter of activated platelets, has been associated with a poor prognosis in BC. We aim to investigate the prognostic role of PDW for bone metastasis in BC patients. 515 patients who received BC surgery in the Harbin Medical University Cancer Hospital from July 1, 2016, to December 31, 2017, were reviewed. Patients' characteristics and platelet indices upon enrollment in this study were collected. The Kaplan-Meier method was used to estimate the 5-year bone metastasis incidence. The univariate and multivariate Cox regression analyses were utilized to identify risk factors associated with bone metastasis. The patients with bone metastases exhibited lower PDW levels than the patients without bone metastases. Moreover, decreased PDW was significantly correlated with histologic type, multifocal disease, and lymph node status. In addition, the patients with reduced PDW levels were more likely to develop bone metastasis. Multivariate analysis showed that PDW was an independent predictor for bone metastasis. PDW is an independent predictor of bone metastasis in BC. Further research is warranted.
Bone metastases occur in 50-70% of patients with breast cancer (BC) and result in high mortality. Platelet distribution width (PDW), a commonly used parameter of activated platelets, has been associated with a poor prognosis in BC. We aim to investigate the prognostic role of PDW for bone metastasis in BC patients. 515 patients who received BC surgery in the Harbin Medical University Cancer Hospital from July 1, 2016, to December 31, 2017, were reviewed. Patients' characteristics and platelet indices upon enrollment in this study were collected. The Kaplan-Meier method was used to estimate the 5-year bone metastasis incidence. The univariate and multivariate Cox regression analyses were utilized to identify risk factors associated with bone metastasis. The patients with bone metastases exhibited lower PDW levels than the patients without bone metastases. Moreover, decreased PDW was significantly correlated with histologic type, multifocal disease, and lymph node status. In addition, the patients with reduced PDW levels were more likely to develop bone metastasis. Multivariate analysis showed that PDW was an independent predictor for bone metastasis. PDW is an independent predictor of bone metastasis in BC. Further research is warranted.
Bone metastases occur in 50-70% of patients with breast cancer (BC) and result in high mortality. Platelet distribution width (PDW), a commonly used parameter of activated platelets, has been associated with a poor prognosis in BC. We aim to investigate the prognostic role of PDW for bone metastasis in BC patients.PURPOSEBone metastases occur in 50-70% of patients with breast cancer (BC) and result in high mortality. Platelet distribution width (PDW), a commonly used parameter of activated platelets, has been associated with a poor prognosis in BC. We aim to investigate the prognostic role of PDW for bone metastasis in BC patients.515 patients who received BC surgery in the Harbin Medical University Cancer Hospital from July 1, 2016, to December 31, 2017, were reviewed. Patients' characteristics and platelet indices upon enrollment in this study were collected. The Kaplan-Meier method was used to estimate the 5-year bone metastasis incidence. The univariate and multivariate Cox regression analyses were utilized to identify risk factors associated with bone metastasis.METHODS515 patients who received BC surgery in the Harbin Medical University Cancer Hospital from July 1, 2016, to December 31, 2017, were reviewed. Patients' characteristics and platelet indices upon enrollment in this study were collected. The Kaplan-Meier method was used to estimate the 5-year bone metastasis incidence. The univariate and multivariate Cox regression analyses were utilized to identify risk factors associated with bone metastasis.The patients with bone metastases exhibited lower PDW levels than the patients without bone metastases. Moreover, decreased PDW was significantly correlated with histologic type, multifocal disease, and lymph node status. In addition, the patients with reduced PDW levels were more likely to develop bone metastasis. Multivariate analysis showed that PDW was an independent predictor for bone metastasis.RESULTSThe patients with bone metastases exhibited lower PDW levels than the patients without bone metastases. Moreover, decreased PDW was significantly correlated with histologic type, multifocal disease, and lymph node status. In addition, the patients with reduced PDW levels were more likely to develop bone metastasis. Multivariate analysis showed that PDW was an independent predictor for bone metastasis.PDW is an independent predictor of bone metastasis in BC. Further research is warranted.CONCLUSIONPDW is an independent predictor of bone metastasis in BC. Further research is warranted.
ArticleNumber 1066
Audience Academic
Author Wang, Rui-Tao
Zhang, Xin
Cui, Ming-Ming
Song, Mei-Yue
Liu, Yu-Xi
Zhao, Lin
Huang, Wen-Juan
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Cites_doi 10.1155/2015/764250
10.3233/CBM-181267
10.1001/jama.2016.0287
10.1186/1748-717X-8-121
10.3389/fonc.2021.764119
10.1097/CEJ.0000000000000440
10.2147/CMAR.S418574
10.1073/pnas.1411082111
10.12659/MSM.904916
10.1182/blood.V89.2.577
10.3389/fonc.2022.855609
10.1182/blood.2019004119
10.1111/j.1471-0528.2011.03239.x
10.1177/1533033819837261
10.21037/tcr.2019.07.28
10.1111/nep.12679
10.1038/s41388-021-01956-6
10.1182/blood-2014-08-595686
10.3390/ijms22062898
10.1007/s12288-021-01411-2
10.1172/JCI200422123
10.1371/journal.pone.0104730
10.1177/1559325819874199
10.1186/cc2893
10.1016/j.phrs.2023.106777
10.1007/s12282-019-00976-1
10.1016/j.celrep.2023.113147
10.1182/blood.2023020535
10.2147/CMAR.S155524
10.3390/ijms232012221
10.1016/j.ccr.2011.09.009
10.1016/j.ijcard.2019.02.054
10.1073/pnas.0700625104
10.1089/sur.2017.278
10.1186/2001-1326-1-16
10.1007/s12032-014-0217-z
10.1007/s12288-014-0365-5
10.1186/s12964-019-0464-x
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Issue 1
Keywords Bone metastasis
Breast cancer
Platelet distribution width
Language English
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References Y Huang (12837_CR19) 2018; 23
Z Xiong (12837_CR6) 2018; 10
K Bin Waleed (12837_CR35) 2019; 285
AT Bauer (12837_CR25) 2015; 125
X Song (12837_CR31) 2022; 12
CD Acosta (12837_CR2) 2012; 119
M Labelle (12837_CR33) 2011; 20
S Lazar (12837_CR23) 2021; 137
W Qian (12837_CR42) 2019; 18
DA Yardley (12837_CR4) 2016; 8
L Wang (12837_CR32) 2023; 15
12837_CR21
X Zhang (12837_CR30) 2023; 191
MD Williams (12837_CR7) 2004; 8
MG Netea (12837_CR16) 1997; 89
YP Hsieh (12837_CR17) 2017; 22
H Lin (12837_CR9) 2013; 8
JJ Wang (12837_CR40) 2019; 18
W Zhang (12837_CR20) 2023; 42
X Jin (12837_CR3) 2015; 9
XX Zuo (12837_CR34) 2019; 17
M Singer (12837_CR13) 2016; 315
JM Wang (12837_CR43) 2019; 17
U Sevuk (12837_CR38) 2015; 31
M Labelle (12837_CR27) 2014; 111
N Li (12837_CR18) 2019; 26
S Takagi (12837_CR26) 2021; 40
12837_CR5
M Stotz (12837_CR10) 2014; 9
J Yu (12837_CR39) 2017; 23
DJ Sharma (12837_CR36) 2023; 15
LM Napolitano (12837_CR1) 2018; 19
12837_CR8
A Boucharaba (12837_CR28) 2004; 114
YJ Lu (12837_CR41) 2019; 8
MA Fini (12837_CR15) 2012; 1
12837_CR11
S Jain (12837_CR24) 2007; 104
F Dovell (12837_CR14) 2018; 27
R Kaiser (12837_CR29) 2023; 142
L Yu (12837_CR22) 2021; 11
S Mangalesh (12837_CR37) 2021; 37
NN Abou-Mourad (12837_CR12) 1979; 148
References_xml – ident: 12837_CR8
  doi: 10.1155/2015/764250
– volume: 23
  start-page: 205
  issue: 2
  year: 2018
  ident: 12837_CR19
  publication-title: Cancer Biomark A
  doi: 10.3233/CBM-181267
  contributor:
    fullname: Y Huang
– volume: 8
  start-page: 73
  year: 2016
  ident: 12837_CR4
  publication-title: Breast cancer (Dove Med Press)
  contributor:
    fullname: DA Yardley
– volume: 315
  start-page: 801
  issue: 8
  year: 2016
  ident: 12837_CR13
  publication-title: JAMA
  doi: 10.1001/jama.2016.0287
  contributor:
    fullname: M Singer
– volume: 8
  start-page: 121
  year: 2013
  ident: 12837_CR9
  publication-title: Radiation Oncol (London England)
  doi: 10.1186/1748-717X-8-121
  contributor:
    fullname: H Lin
– volume: 11
  start-page: 764119
  year: 2021
  ident: 12837_CR22
  publication-title: Front Oncol
  doi: 10.3389/fonc.2021.764119
  contributor:
    fullname: L Yu
– volume: 27
  start-page: 399
  issue: 4
  year: 2018
  ident: 12837_CR14
  publication-title: Eur J cancer Prevention: Official J Eur Cancer Prev Organisation (ECP)
  doi: 10.1097/CEJ.0000000000000440
  contributor:
    fullname: F Dovell
– volume: 15
  start-page: 811
  year: 2023
  ident: 12837_CR32
  publication-title: Cancer Manage Res
  doi: 10.2147/CMAR.S418574
  contributor:
    fullname: L Wang
– volume: 111
  start-page: E3053
  issue: 30
  year: 2014
  ident: 12837_CR27
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.1411082111
  contributor:
    fullname: M Labelle
– volume: 23
  start-page: 5899
  year: 2017
  ident: 12837_CR39
  publication-title: Med Sci Monit
  doi: 10.12659/MSM.904916
  contributor:
    fullname: J Yu
– volume: 89
  start-page: 577
  issue: 2
  year: 1997
  ident: 12837_CR16
  publication-title: Blood
  doi: 10.1182/blood.V89.2.577
  contributor:
    fullname: MG Netea
– volume: 12
  start-page: 855609
  year: 2022
  ident: 12837_CR31
  publication-title: Front Oncol
  doi: 10.3389/fonc.2022.855609
  contributor:
    fullname: X Song
– volume: 137
  start-page: 3192
  issue: 23
  year: 2021
  ident: 12837_CR23
  publication-title: Blood
  doi: 10.1182/blood.2019004119
  contributor:
    fullname: S Lazar
– volume: 9
  start-page: 23
  issue: Suppl 1
  year: 2015
  ident: 12837_CR3
  publication-title: Breast cancer: Basic Clin Res
  contributor:
    fullname: X Jin
– volume: 119
  start-page: 474
  issue: 4
  year: 2012
  ident: 12837_CR2
  publication-title: BJOG: Int J Obstet Gynecol
  doi: 10.1111/j.1471-0528.2011.03239.x
  contributor:
    fullname: CD Acosta
– volume: 18
  start-page: 153303381983726
  year: 2019
  ident: 12837_CR40
  publication-title: Technol Cancer Res Treat
  doi: 10.1177/1533033819837261
  contributor:
    fullname: JJ Wang
– volume: 8
  start-page: 1326
  issue: 4
  year: 2019
  ident: 12837_CR41
  publication-title: Transl Cancer Res
  doi: 10.21037/tcr.2019.07.28
  contributor:
    fullname: YJ Lu
– volume: 22
  start-page: 441
  issue: 6
  year: 2017
  ident: 12837_CR17
  publication-title: Nephrol (Carlton Vic)
  doi: 10.1111/nep.12679
  contributor:
    fullname: YP Hsieh
– volume: 40
  start-page: 5548
  issue: 36
  year: 2021
  ident: 12837_CR26
  publication-title: Oncogene
  doi: 10.1038/s41388-021-01956-6
  contributor:
    fullname: S Takagi
– volume: 18
  start-page: 571
  issue: 1
  year: 2019
  ident: 12837_CR42
  publication-title: Oncol Lett
  contributor:
    fullname: W Qian
– volume: 125
  start-page: 3153
  issue: 20
  year: 2015
  ident: 12837_CR25
  publication-title: Blood
  doi: 10.1182/blood-2014-08-595686
  contributor:
    fullname: AT Bauer
– ident: 12837_CR5
  doi: 10.3390/ijms22062898
– volume: 37
  start-page: 600
  issue: 4
  year: 2021
  ident: 12837_CR37
  publication-title: Indian J Hematol Blood Transfus
  doi: 10.1007/s12288-021-01411-2
  contributor:
    fullname: S Mangalesh
– volume: 114
  start-page: 1714
  issue: 12
  year: 2004
  ident: 12837_CR28
  publication-title: J Clin Invest
  doi: 10.1172/JCI200422123
  contributor:
    fullname: A Boucharaba
– volume: 9
  start-page: e104730
  issue: 8
  year: 2014
  ident: 12837_CR10
  publication-title: PLoS ONE
  doi: 10.1371/journal.pone.0104730
  contributor:
    fullname: M Stotz
– volume: 17
  start-page: 155932581987419
  issue: 3
  year: 2019
  ident: 12837_CR43
  publication-title: Dose Response
  doi: 10.1177/1559325819874199
  contributor:
    fullname: JM Wang
– volume: 148
  start-page: 358
  issue: 3
  year: 1979
  ident: 12837_CR12
  publication-title: Surg Gynecol Obstet
  contributor:
    fullname: NN Abou-Mourad
– volume: 8
  start-page: R291
  issue: 5
  year: 2004
  ident: 12837_CR7
  publication-title: Crit Care (London England)
  doi: 10.1186/cc2893
  contributor:
    fullname: MD Williams
– volume: 191
  start-page: 106777
  year: 2023
  ident: 12837_CR30
  publication-title: Pharmacol Res
  doi: 10.1016/j.phrs.2023.106777
  contributor:
    fullname: X Zhang
– volume: 26
  start-page: 712
  issue: 6
  year: 2019
  ident: 12837_CR18
  publication-title: Breast cancer (Tokyo Japan)
  doi: 10.1007/s12282-019-00976-1
  contributor:
    fullname: N Li
– volume: 42
  start-page: 113147
  issue: 9
  year: 2023
  ident: 12837_CR20
  publication-title: Cell Rep
  doi: 10.1016/j.celrep.2023.113147
  contributor:
    fullname: W Zhang
– volume: 142
  start-page: 1413
  issue: 17
  year: 2023
  ident: 12837_CR29
  publication-title: Blood
  doi: 10.1182/blood.2023020535
  contributor:
    fullname: R Kaiser
– volume: 10
  start-page: 287
  year: 2018
  ident: 12837_CR6
  publication-title: Cancer Manage Res
  doi: 10.2147/CMAR.S155524
  contributor:
    fullname: Z Xiong
– ident: 12837_CR21
  doi: 10.3390/ijms232012221
– volume: 20
  start-page: 576
  issue: 5
  year: 2011
  ident: 12837_CR33
  publication-title: Cancer Cell
  doi: 10.1016/j.ccr.2011.09.009
  contributor:
    fullname: M Labelle
– volume: 285
  start-page: 128
  year: 2019
  ident: 12837_CR35
  publication-title: Int J Cardiol
  doi: 10.1016/j.ijcard.2019.02.054
  contributor:
    fullname: K Bin Waleed
– volume: 15
  start-page: e38095
  issue: 4
  year: 2023
  ident: 12837_CR36
  publication-title: Cureus
  contributor:
    fullname: DJ Sharma
– volume: 104
  start-page: 9024
  issue: 21
  year: 2007
  ident: 12837_CR24
  publication-title: Proc Natl Acad Sci U S A
  doi: 10.1073/pnas.0700625104
  contributor:
    fullname: S Jain
– volume: 19
  start-page: 117
  issue: 2
  year: 2018
  ident: 12837_CR1
  publication-title: Surg Infect
  doi: 10.1089/sur.2017.278
  contributor:
    fullname: LM Napolitano
– volume: 1
  start-page: 16
  issue: 1
  year: 2012
  ident: 12837_CR15
  publication-title: Clin Translational Med
  doi: 10.1186/2001-1326-1-16
  contributor:
    fullname: MA Fini
– ident: 12837_CR11
  doi: 10.1007/s12032-014-0217-z
– volume: 31
  start-page: 71
  issue: 1
  year: 2015
  ident: 12837_CR38
  publication-title: Indian J Hematol Blood Transfus
  doi: 10.1007/s12288-014-0365-5
  contributor:
    fullname: U Sevuk
– volume: 17
  start-page: 142
  issue: 1
  year: 2019
  ident: 12837_CR34
  publication-title: Cell Communication Signaling: CCS
  doi: 10.1186/s12964-019-0464-x
  contributor:
    fullname: XX Zuo
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Snippet Bone metastases occur in 50-70% of patients with breast cancer (BC) and result in high mortality. Platelet distribution width (PDW), a commonly used parameter...
Purpose Bone metastases occur in 50-70% of patients with breast cancer (BC) and result in high mortality. Platelet distribution width (PDW), a commonly used...
PurposeBone metastases occur in 50-70% of patients with breast cancer (BC) and result in high mortality. Platelet distribution width (PDW), a commonly used...
Abstract Purpose Bone metastases occur in 50-70% of patients with breast cancer (BC) and result in high mortality. Platelet distribution width (PDW), a...
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SourceType Open Website
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Index Database
StartPage 1066
SubjectTerms Adult
Aged
Analysis
Blood platelets
Blood Platelets - pathology
Bone cancer
Bone metastasis
Bone Neoplasms - blood
Bone Neoplasms - secondary
Bone surgery
Breast cancer
Breast Neoplasms - blood
Breast Neoplasms - pathology
Cancer
Cancer patients
Cancer therapies
Care and treatment
Development and progression
Diagnosis
Disease susceptibility
Endothelium
Female
Females
Growth factors
Health aspects
Hemoglobin
Hospitals
Humans
Kaplan-Meier Estimate
Lymph nodes
Lymphatic system
Measurement
Medical colleges
Medical prognosis
Metastases
Metastasis
Middle Aged
Multivariate analysis
Oncology, Experimental
Ovarian cancer
Patients
Platelet Count
Platelet distribution width
Platelets
Preoperative Period
Prognosis
Retrospective Studies
Risk Factors
Surgery
Tomography
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Title Preoperative platelet distribution width predicts bone metastasis in patients with breast cancer
URI https://www.ncbi.nlm.nih.gov/pubmed/39210343
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https://www.proquest.com/docview/3099800906
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Volume 24
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