The Sw-5 Gene Cluster: Tomato Breeding and Research Toward Orthotospovirus Disease Control
The gene cluster encodes protein receptors that are potentially able to recognize microbial products and activate signaling pathways that lead to plant cell immunity. Although there are several homologs in the tomato genome, only one of them, named , has been extensively studied due to its functiona...
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Published in | Frontiers in plant science Vol. 9; p. 1055 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Switzerland
Frontiers Media S.A
19.07.2018
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Subjects | |
Online Access | Get full text |
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Summary: | The
gene cluster encodes protein receptors that are potentially able to recognize microbial products and activate signaling pathways that lead to plant cell immunity. Although there are several
homologs in the tomato genome, only one of them, named
, has been extensively studied due to its functionality against a wide range of (thrips-transmitted) orthotospoviruses. The
gene is a dominant resistance gene originally from a wild Peruvian tomato that has been used in tomato breeding programs aiming to develop cultivars with resistance to these viruses. Here, we provide an overview starting from the first reports of Sw-5 resistance, positional cloning and the sequencing of the
gene cluster from resistant tomatoes and the validation of Sw-5b as the functional protein that triggers resistance against orthotospoviruses. Moreover, molecular details of this plant-virus interaction are also described, especially concerning the roles of Sw-5b domains in the sensing of orthotospoviruses and in the signaling cascade leading to resistance and hypersensitive response. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Reviewed by: Gian Paolo Accotto, Istituto per la Protezione Sostenibile delle Piante (IPSP), Italy; Denis Michael Persley, Queensland Government, Australia This article was submitted to Virology, a section of the journal Frontiers in Plant Science Edited by: Ralf Georg Dietzgen, The University of Queensland, Australia |
ISSN: | 1664-462X 1664-462X |
DOI: | 10.3389/fpls.2018.01055 |