The determination of a dose deposited in reference medium due to (p,n) reaction occurring during proton therapy

• Published in: Reports of practical oncology and radiotherapy Vol. 19; no. Suppl; pp. S3 - S8
• Main Authors: Dawidowska, Anna, Ferszt, Monika Paluch, Konefał, Adam
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Urban & Partner Sp. z.o.o 01.05.2014
• Subjects: GEANT4; Hematology, Oncology and Palliative Medicine; Monte Carlo; Neutrons; Original; Proton therapy; Radiology; Neutrons; GEANT4; Proton therapy; Monte Carlo
• ISSN: 1507-1367; 2083-4640
• DOI: 10.1016/j.rpor.2014.02.003

Abstract Aim The aim of the investigation was to determine the undesirable dose coming from neutrons produced in reactions (p,n) in irradiated tissues represented by water. Background Production of neutrons in the system of beam collimators and in irradiated tissues is the undesirable phenomenon related to the application of protons in radiotherapy. It makes that proton beams are contaminated by neutrons and patients receive the undesirable neutron dose. Materials and methods The investigation was based on the Monte Carlo simulations (GEANT4 code). The calculations were performed for five energies of protons: 50 MeV, 55 MeV, 60 MeV, 65 MeV and 75 MeV. The neutron doses were calculated on the basis of the neutron fluence and neutron energy spectra derived from simulations and by means of the neutron fluence–dose conversion coefficients taken from the ICRP dosimetry protocol no. 74 for the antero-posterior irradiation geometry. Results The obtained neutron doses are much less than the proton ones. They do not exceed 0.1%, 0.4%, 0.5%, 0.6% and 0.7% of the total dose at a given depth for the primary protons with energy of 50 MeV, 55 MeV, 60 MeV, 65 MeV and 70 MeV, respectively. Conclusions The neutron production takes place mainly along the central axis of the beam. The maximum neutron dose appears at about a half of the depth of the maximum proton dose (Bragg peak), i.e. in the volume of a healthy tissue. The doses of neutrons produced in the irradiated medium (water) are about two orders of magnitude less than the proton doses for the considered range of energy of protons.