Nonsurgical orthodontic treatment for a patient with Sotos syndrome

• Published in: American journal of orthodontics and dentofacial orthopedics Vol. 163; no. 3; pp. 426 - 442
• Main Authors: Shioyasono, Ryoko, Yoshinaga, Kaoru, Shioyasono, Atsushi, Ito, Ayami, Watanabe, Keiichiro, Hiasa, Masahiro, Horiuchi, Shinya, Tanaka, Eiji
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.03.2023
• Subjects: Cephalometry; Child; Dentistry; Extraoral Traction Appliances; Humans; Male; Malocclusion; Malocclusion, Angle Class III - therapy; Mandible; Maxilla; Palatal Expansion Technique; Sotos Syndrome
• ISSN: 0889-5406; 1097-6752; 1097-6752
• DOI: 10.1016/j.ajodo.2021.11.021

Sotos syndrome is a genetic disorder characterized by overgrowth in childhood, specific facial manifestations, advanced bone age, and mental retardation. The purpose of this article is to describe the nonsurgical orthodontic treatment of a 10-year-old boy with a skeletal mandibular protrusion, unilateral posterior crossbite, and Sotos syndrome. After maxillary lateral expansion, the skeletal Class III relationship with an anterior crossbite improved because of mandibular clockwise rotation, whereas the facemask had a marginal effect. After growth at 16 years, he had a skeletal Class I relationship, and thus, conventional orthodontic treatment with preadjusted edgewise appliances was initiated. After 41 months of multibracket treatment, acceptable occlusion with a functional Class I relationship was obtained. One year postretention, few changes in occlusion and facial features were observed. Our results demonstrate that considering the maxillofacial vertical growth during the peripubertal period associated with Sotos syndrome, more attention should be paid to the early orthopedic treatment with the facemask and/or chincap. •Sotos syndrome is an overgrowth syndrome that presents prenatally.•Long-term follow-up of an orthodontic patient with Sotos syndrome is reported.•Skeletal Class III malocclusion was corrected without surgery.•Early orthopedic treatment with the facemask or chincap can be beneficial.