Prodrug-based nanoparticulate drug delivery strategies for cancer therapy

Highlights • Recent trends in prodrug-based nanocarriers for cancer therapy are provided. • Stimuli-sensitive nanoparticulate drug delivery systems (Nano-DDS) facilitates the spatio-temporally controlled release of drugs. • Hybrid Nano-DDS is a potent multifunctional platform to deliver anticancer d...

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Bibliographic Details
Published inTrends in pharmacological sciences (Regular ed.) Vol. 35; no. 11; pp. 556 - 566
Main Authors Luo, Cong, Sun, Jin, Sun, Bingjun, He, Zhonggui
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.11.2014
Subjects
Advanced Basic Science
Animals
Antineoplastic Agents - administration & dosage
Antineoplastic Agents - chemistry
cancer therapy
combination therapy
Drug Carriers - administration & dosage
Drug Carriers - chemistry
Drug Delivery Systems - methods
Humans
hybrid nanoassemblies
Nanoparticles - administration & dosage
Nanoparticles - chemistry
Neoplasms - drug therapy
prodrug nanoassemblies
Prodrugs - administration & dosage
Prodrugs - chemistry
stimuli-responsive
cancer therapy
hybrid nanoassemblies
combination therapy
stimuli-responsive
prodrug nanoassemblies
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Summary:Highlights • Recent trends in prodrug-based nanocarriers for cancer therapy are provided. • Stimuli-sensitive nanoparticulate drug delivery systems (Nano-DDS) facilitates the spatio-temporally controlled release of drugs. • Hybrid Nano-DDS is a potent multifunctional platform to deliver anticancer drugs. • Combination therapy can improve the therapeutic effects of prodrug-based Nano-DDS.
Bibliography:ObjectType-Article-2
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ObjectType-Review-1
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ISSN:0165-6147
1873-3735
DOI:10.1016/j.tips.2014.09.008