A review on microfabrication of thermoplastic polymer‐based microneedle arrays
This article will provide an overview of recent developments for microneedles made using injection molding and hot embossing techniques for active transdermal drug delivery. Microneedle arrays are developed for pain‐free and efficient drug delivery without using a cold chain. The focus of this artic...
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| Published in | Polymer engineering and science Vol. 59; no. 5; pp. 877 - 890 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
Hoboken, USA
John Wiley & Sons, Inc
01.05.2019
Society of Plastics Engineers, Inc Blackwell Publishing Ltd |
| Subjects | |
| Online Access | Get full text |
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| Abstract | This article will provide an overview of recent developments for microneedles made using injection molding and hot embossing techniques for active transdermal drug delivery. Microneedle arrays are developed for pain‐free and efficient drug delivery without using a cold chain. The focus of this article will be on the use of engineering thermoplastics and microneedle manufacturing techniques including patterning. Recent developments demonstrate that commercialization of polymer‐based microneedle systems is feasible. POLYM. ENG. SCI., 59:877–890, 2019. © 2019 Society of Plastics Engineers |
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| AbstractList | This article will provide an overview of recent developments for microneedles made using injection molding and hot embossing techniques for active transdermal drug delivery. Microneedle arrays are developed for pain‐free and efficient drug delivery without using a cold chain. The focus of this article will be on the use of engineering thermoplastics and microneedle manufacturing techniques including patterning. Recent developments demonstrate that commercialization of polymer‐based microneedle systems is feasible. POLYM. ENG. SCI., 59:877–890, 2019. © 2019 Society of Plastics Engineers This article will provide an overview of recent developments for microneedles made using injection molding and hot embossing techniques for active transdermal drug delivery. Microneedle arrays are developed for pain-free and efficient drug delivery without using a cold chain. The focus of this article will be on the use of engineering thermoplastics and microneedle manufacturing techniques including patterning. Recent developments demonstrate that commercialization of polymer-based microneedle systems is feasible. |
| Audience | Academic |
| Author | Brouwer, Hans Juster, Herwig Aar, Bart |
| Author_xml | – sequence: 1 givenname: Herwig orcidid: 0000-0002-1495-2286 surname: Juster fullname: Juster, Herwig email: herwig.juster@gmail.com organization: SABIC – sequence: 2 givenname: Bart surname: Aar fullname: Aar, Bart organization: SABIC – sequence: 3 givenname: Hans surname: Brouwer fullname: Brouwer, Hans organization: SABIC |
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| Snippet | This article will provide an overview of recent developments for microneedles made using injection molding and hot embossing techniques for active transdermal... |
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| SubjectTerms | Commercialization Drug delivery systems Embossing Equipment and supplies Hypodermic needles Injection molding Medical personnel Methods Microneedle drug delivery Pain Polymer industry Polymers Production management Production processes Thermoplastic resins Thermoplastics Topical analgesics Transdermal drug delivery systems Transdermal medication |
| Title | A review on microfabrication of thermoplastic polymer‐based microneedle arrays |
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