A review on microfabrication of thermoplastic polymer‐based microneedle arrays

This article will provide an overview of recent developments for microneedles made using injection molding and hot embossing techniques for active transdermal drug delivery. Microneedle arrays are developed for pain‐free and efficient drug delivery without using a cold chain. The focus of this artic...

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Bibliographic Details
Published inPolymer engineering and science Vol. 59; no. 5; pp. 877 - 890
Main Authors Juster, Herwig, Aar, Bart, Brouwer, Hans
Format Journal Article
LanguageEnglish
Published Hoboken, USA John Wiley & Sons, Inc 01.05.2019
Society of Plastics Engineers, Inc
Blackwell Publishing Ltd
Subjects
Commercialization
Drug delivery systems
Embossing
Equipment and supplies
Hypodermic needles
Injection molding
Medical personnel
Methods
Microneedle drug delivery
Pain
Polymer industry
Polymers
Production management
Production processes
Thermoplastic resins
Thermoplastics
Topical analgesics
Transdermal drug delivery systems
Transdermal medication
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Summary:This article will provide an overview of recent developments for microneedles made using injection molding and hot embossing techniques for active transdermal drug delivery. Microneedle arrays are developed for pain‐free and efficient drug delivery without using a cold chain. The focus of this article will be on the use of engineering thermoplastics and microneedle manufacturing techniques including patterning. Recent developments demonstrate that commercialization of polymer‐based microneedle systems is feasible. POLYM. ENG. SCI., 59:877–890, 2019. © 2019 Society of Plastics Engineers
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0032-3888
1548-2634
DOI:10.1002/pen.25078