Merging Visible‐Light Catalysis for the Direct Late‐Stage Group‐16–Trifluoromethyl Bond Formation

The use of visible light activation/photoredox chemistry for the generation of radical‐centered chalcogen–CF3 has gained widespread interest in the last past three years. Its subsequent reactivity for the synthesis of new chalcogen–CF3‐containing building blocks gained much attention. To date severa...

Full description

Saved in:
Bibliographic Details
Published inChemistry : a European journal Vol. 25; no. 26; pp. 6482 - 6495
Main Authors Ghiazza, Clément, Billard, Thierry, Tlili, Anis
Format Journal Article
LanguageEnglish
Published Germany Wiley Subscription Services, Inc 07.05.2019
Wiley-VCH Verlag
Subjects
Catalysis
chalcogens
Chemical Sciences
Chemistry
fluorine
Organic chemistry
photoredox
Reaction mechanisms
Substrates
trifluoromethyl
catalysis
trifluoromethyl
photoredox
chalcogens
fluorine
Online AccessGet full text

Cover

More Information
Summary:The use of visible light activation/photoredox chemistry for the generation of radical‐centered chalcogen–CF3 has gained widespread interest in the last past three years. Its subsequent reactivity for the synthesis of new chalcogen–CF3‐containing building blocks gained much attention. To date several methodologies have been developed addressing several challenges in modern organofluorine chemistry and enabled substantial progress in substrates scope and reaction conditions. This review describes these advancements with a particular focus on the reaction mechanisms. The use of visible‐light/photoredox catalysis emerged recently as a powerful tool for the generation of chalcogen trifluoromethyl‐centred radicals and their subsequent incorporation in organic building blocks. The developed methodologies are highlighted herein.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.201806234