Epigenomic dynamics of early Xenopus Embryos
How the embryonic genome regulates accessibility to transcription factors is one of the major questions in understanding the spatial and temporal dynamics of gene expression during embryogenesis. Epigenomic analyses of embryonic chromatin provide molecular insights into cell‐specific gene activities...
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Published in | Development, growth & differentiation Vol. 64; no. 9; pp. 508 - 516 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Japan
Wiley Subscription Services, Inc
01.12.2022
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Subjects | |
Online Access | Get full text |
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Summary: | How the embryonic genome regulates accessibility to transcription factors is one of the major questions in understanding the spatial and temporal dynamics of gene expression during embryogenesis. Epigenomic analyses of embryonic chromatin provide molecular insights into cell‐specific gene activities and genomic architectures. In recent years, significant advances have been made to elucidate the dynamic changes behind the activation of the zygotic genome in various model organisms. Here we provide an overview of the recent epigenomic studies pertaining to early Xenopus development. |
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Bibliography: | Funding information National Institutes of Health, Grant/Award Numbers: R01GM126395, R35GM139617; National Science Foundation, Grant/Award Number: 1755214 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
ISSN: | 0012-1592 1440-169X |
DOI: | 10.1111/dgd.12813 |