Ultrasound‐controlled transthoracic true‐cut needle biopsy in pulmonary nodular amyloidosis

• Published in: Respirology case reports Vol. 11; no. 6; pp. e01142 - n/a
• Main Authors: Mihalova, Teodora Z., Ivanova, Silviya S., Mekov, Evgeni V., Yamakova, Yordanka Т., Petkov, Rosen E.
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 01.06.2023; John Wiley & Sons, Inc; Wiley
• Subjects: Abdomen; Amyloidosis; Biopsy; Case Report; Case Reports; Disease; Laboratories; Lungs; Lymphoma; Medical imaging; Ostomy; pulmonary amyloidosis; Thorax; true‐cut biopsy; Tuberculosis; Tumors; Ultrasonic imaging; ultrasound‐controlled; true‐cut biopsy; pulmonary amyloidosis; ultrasound‐controlled
• ISSN: 2051-3380; 2051-3380
• DOI: 10.1002/rcr2.1142

The current case report presents a 59‐year‐old man with imaging studies of the thorax showing nodular lesions in the lungs bilaterally. Based on radiographic and CT images, preliminary diagnoses for possible granulomatosis (tuberculosis) or pulmonary metastatic dissemination of a neoplastic process were made. An ultrasound‐controlled transthoracic true‐cut needle biopsy of a subpleural lesion was performed. Special staining with Congo red and examination with a polarizing light microscope for detection of amyloid confirmed the diagnosis of ‘pulmonary nodular amyloidosis’ by visualizing green birefringence. The current case report presents a 59‐year‐old man with imaging studies of the thorax showing nodular lesions in the lungs bilaterally. Preliminary diagnoses for possible granulomatosis (tuberculosis) or pulmonary metastatic dissemination of a neoplastic process were made. An ultrasound‐controlled transthoracic true‐cut needle biopsy of a subpleural lesion was performed, confirming the diagnosis of ‘pulmonary nodular amyloidosis’.