Neuromuscular blocking agents in the intensive care unit

Neuromuscular blocking agents (NMBA) are a controversial therapeutic option in the approach to the critically ill patient. They are not innocuous, and the available evidence does not support their routine use in the intensive care unit. If necessary, monitoring protocols should be established to avo...

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Published inJournal of International Medical Research Vol. 50; no. 9; pp. 30006052211281 - 3000605221128148
Main Authors Rodríguez-Blanco, Jonathan, Rodríguez-Yanez, Tomás, Rodríguez-Blanco, Jesús Daniel, Almanza-Hurtado, Amilkar José, Martínez-Ávila, María Cristina, Borré-Naranjo, Diana, Acuña Caballero, María Camila, Dueñas-Castell, Carmelo
Format Book Review Journal Article
LanguageEnglish
Published London, England SAGE Publications 01.09.2022
Sage Publications Ltd
SAGE Publishing
Subjects
Intensive care
Neuromuscular system
Review
Neuromuscular blocking agent
intensive care unit
train of four
post-tetanic count
review
muscle weakness
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Summary:Neuromuscular blocking agents (NMBA) are a controversial therapeutic option in the approach to the critically ill patient. They are not innocuous, and the available evidence does not support their routine use in the intensive care unit. If necessary, monitoring protocols should be established to avoid residual relaxation, adverse effects, and associated complications. This narrative review discusses the current indications for the use of NMBA and the different tools for monitoring blockade in the intensive care unit. However, expanding the use of NMBA in critical settings merits the development of prospective studies.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0300-0605
1473-2300
DOI:10.1177/03000605221128148