Speed of synchronization in complex networks of neural oscillators: Analytic results based on Random Matrix Theory

• Published in: Chaos (Woodbury, N.Y.) Vol. 16; no. 1; pp. 015108 - 15122
• Main Authors: Timme, Marc, Geisel, Theo, Wolf, Fred
• Format: Journal Article
• Language: English
• Published: United States 01.03.2006
• Subjects: Action Potentials - physiology; Algorithms; Animals; Biological Clocks - physiology; Computer Simulation; Humans; Models, Neurological; Models, Statistical; Nerve Net - physiology; Neurons - physiology; Nonlinear Dynamics; Synaptic Transmission - physiology; Time Factors
• ISSN: 1054-1500; 1089-7682
• DOI: 10.1063/1.2150775

We analyze the dynamics of networks of spiking neural oscillators. First, we present an exact linear stability theory of the synchronous state for networks of arbitrary connectivity. For general neuron rise functions, stability is determined by multiple operators, for which standard analysis is not suitable. We describe a general nonstandard solution to the multioperator problem. Subsequently, we derive a class of neuronal rise functions for which all stability operators become degenerate and standard eigenvalue analysis becomes a suitable tool. Interestingly, this class is found to consist of networks of leaky integrate-and-fire neurons. For random networks of inhibitory integrate-and-fire neurons, we then develop an analytical approach, based on the theory of random matrices, to precisely determine the eigenvalue distributions of the stability operators. This yields the asymptotic relaxation time for perturbations to the synchronous state which provides the characteristic time scale on which neurons can coordinate their activity in such networks. For networks with finite in-degree, i.e., finite number of presynaptic inputs per neuron, we find a speed limit to coordinating spiking activity. Even with arbitrarily strong interaction strengths neurons cannot synchronize faster than at a certain maximal speed determined by the typical in-degree.