Using cone-beam CT as a low-dose 3D imaging technique for the extremities: initial experience in 50 subjects

• Published in: Skeletal radiology Vol. 44; no. 6; pp. 797 - 809
• Main Authors: Huang, Ambrose J., Chang, Connie Y., Thomas, Bijoy J., MacMahon, Peter J., Palmer, William E.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.06.2015; Springer; Springer Nature B.V
• Subjects: Cone-Beam Computed Tomography - methods; CT imaging; Extremities - diagnostic imaging; Female; Humans; Imaging; Imaging, Three-Dimensional - methods; Male; Medicine; Medicine & Public Health; Methods; Middle Aged; Multidetector Computed Tomography - methods; Nuclear Medicine; Orthopedics; Pathology; Pilot Projects; Privacy, Right of; Radiation; Radiation Dosage; Radiation Protection - methods; Radiographic Image Enhancement - methods; Radiology; Radiometry; Reproducibility of Results; Scientific Article; Sensitivity and Specificity; Radiation dose; Fracture; Hardware; Computed tomography; Cone-beam computed tomography; Artifact
• ISSN: 0364-2348; 1432-2161; 1432-2161
• DOI: 10.1007/s00256-015-2105-9

Purpose To prospectively evaluate a dedicated extremity cone-beam CT (CBCT) scanner in cases with and without orthopedic hardware by (1) comparing its imaging duration and image quality to those of radiography and multidetector CT (MDCT) and (2) comparing its radiation dose to that of MDCT. Materials and methods Written informed consent was obtained for all subjects for this IRB-approved, HIPAA-compliant study. Fifty subjects with (1) fracture of small bones, (2) suspected intraarticular fracture, (3) fracture at the site of complex anatomy, or (4) a surgical site difficult to assess with radiography alone were recruited and scanned on an extremity CBCT scanner prior to FDA approval. Same-day radiographs were performed in all subjects. Some subjects also underwent MDCT within 1 month of CBCT. Imaging duration and image quality were compared between CBCT and radiographs. Imaging duration, effective radiation dose, and image quality were compared between CBCT and MDCT. Results Fifty-one CBCT scans were performed in 50 subjects. Average imaging duration was shorter for CBCT than radiographs (4.5 min vs. 6.6 min, P = 0.001, n = 51) and MDCT (7.6 min vs. 10.9 min, P = 0.01, n = 7). Average estimated effective radiation dose was less for CBCT than MDCT (0.04 mSv vs. 0.13 mSv, P = 0.02, n = 7). CBCT images yielded more diagnostic information than radiographs in 23/51 cases and more diagnostic information than MDCT in 1/7 cases, although radiographs were superior for detecting hardware complications. Conclusion CBCT performs high-resolution imaging of the extremities using less imaging time than radiographs and MDCT and lower radiation dose than MDCT.