Subversion and exploitation of host cells by mycoplasmas

Mycoplasmas are minute wall-less bacterial parasites that exhibit strict host and tissue specificities. They enter, multiply and survive within the host for extended periods by circumventing host defenses. Their intimate interaction with eukaryotic cells, and in some cases the subsequent invasion in...

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Bibliographic Details
Published inTrends in Microbiology Vol. 6; no. 11; pp. 436 - 440
Main Authors Rottem, Shlomo, Naot, Yehudith
Format Book Review Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.11.1998
Subjects
adherence
Animals
Bacterial Adhesion
cytokine induction
Cytokines - biosynthesis
Escherichia coli
fusion
Humans
invasion
Macrophages - immunology
Membrane Fusion
mitogenicity
Mitogens - immunology
Mollicutes
Monocytes - immunology
Mycoplasma - genetics
Mycoplasma - immunology
Mycoplasma - metabolism
Mycoplasma - physiology
Mycoplasma genitalium
Mycoplasma Infections - immunology
Mycoplasma Infections - metabolism
Mycoplasma Infections - microbiology
Mycoplasma pneumoniae
mycoplasmas
fusion
mollicutes
invasion
adherence
mitogenicity
cytokine induction
mycoplasmas
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Summary:Mycoplasmas are minute wall-less bacterial parasites that exhibit strict host and tissue specificities. They enter, multiply and survive within the host for extended periods by circumventing host defenses. Their intimate interaction with eukaryotic cells, and in some cases the subsequent invasion into or fusion with these cells, mediates cell damage. Mycoplasmas also modulate the activity of host cells by a variety of direct mechanisms and/or indirectly by cytokine-mediated effects.
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ISSN:0966-842X
1878-4380
DOI:10.1016/S0966-842X(98)01358-4