Excavating Neandertal and Denisovan DNA from the genomes of Melanesian individuals

• Published in: Science (American Association for the Advancement of Science) Vol. 352; no. 6282; pp. 235 - 239
• Main Authors: Vernot, Benjamin, Tucci, Serena, Kelso, Janet, Schraiber, Joshua G., Wolf, Aaron B., Gittelman, Rachel M., Dannemann, Michael, Grote, Steffi, McCoy, Rajiv C., Norton, Heather, Scheinfeldt, Laura B., Merriwether, David A., Koki, George, Friedlaender, Jonathan S., Wakefield, Jon, Pääbo, Svante, Akey, Joshua M.
• Format: Journal Article
• Language: English
• Published: United States American Association for the Advancement of Science 08.04.2016; The American Association for the Advancement of Science
• Subjects: Animals; Deoxyribonucleic acid; DNA; DNA - genetics; Genetic Variation; Genome, Human - genetics; Genomes; Hominids; Humans; Melanesia; Neanderthals - genetics; Pacific Island People - genetics; Sequence Analysis, DNA; Melanesia

Although Neandertal sequences that persist in the genomes of modern humans have been identified in Eurasians, comparable studies in people whose ancestors hybridized with both Neandertals and Denisovans are lacking. We developed an approach to identify DNA inherited from multiple archaic hominin anc...