Oral malignant acanthosis nigricans associated with endometrial adenocarcinoma

• Published in: International journal of oral science Vol. 6; no. 4; pp. 247 - 249
• Main Authors: Chu, Han-Wen, Li, Jing-Min, Chen, Guan-Fu, Ma, Jing-Yuan
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.12.2014; Springer Nature B.V; Department of Oral and Maxillofacial Surgery, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China%Hangzhou Stomatological Hospital, Hangzhou, China%Department of Oral Medicine, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China; Nature Publishing Group
• Subjects: Abdominal Neoplasms - secondary; Acanthosis Nigricans - pathology; Adenocarcinoma - secondary; Case Report; Dentistry; Endometrial Neoplasms - pathology; Female; Follow-Up Studies; Humans; Lip Diseases - pathology; Lymphatic Metastasis - pathology; Medicine; Middle Aged; Oral and Maxillofacial Surgery; Orthopedics; Paraneoplastic Syndromes - pathology; Pelvic Neoplasms - secondary; Surgical Orthopedics; 乳头状瘤; 口腔; 子宫内膜癌; 恶性; 病变; 病理学诊断; 病理特点; 腺癌; oral malignant acanthosis nigricans; endometrial adenocarcinoma
• ISSN: 1674-2818; 2049-3169
• DOI: 10.1038/ijos.2014.1

We report a 59-year-old patient with malignant acanthosis nigricans associated with metastasis of endometrial carcinoma. The patient presented papillomatosis lesions that appeared to be benign on multiple skins of body folds, particularly on lips. The lesions in lips and axilla had histological characteristic appearances of acanthosis nigricans, while the masses in abdomen and pelvis were metastasis endometrial adenocarcinoma. The article highlights the importance of biopsy and histopathological diagnosis in presumed benign lesions and the role of doctors in screening for body internal tumors.