The Correlation Between Preoperative Lower Extremity Deep Vein Thrombosis (DVT) and the Time from Injury to Surgery (TFITS)

• Published in: Clinical and applied thrombosis/hemostasis Vol. 28; p. 10760296221108961
• Main Authors: Cong, Yuxuan, Huang, Hai, Zhang, Bin-Fei, Deng, Hongli, Lei, Jinlai, Ke, Chao, Han, Shuang, Zhang, Kun, Wang, Pengfei
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 2022; SAGE PUBLICATIONS, INC; SAGE Publishing
• Subjects: Original Manuscript; Risk factors; Thrombosis; deep vein thrombosis; time from injury to surgery; risk factor; fracture
• ISSN: 1076-0296; 1938-2723
• DOI: 10.1177/10760296221108961

Objective To investigate the correlation between preoperative DVT and the time from injury to surgery (TFITS), and provide a clinical reference for the prevention of preoperative DVT. Patients and methods We collected the clinical data of patients with lower extremities fractures between September 1, 2014, and May 31, 2019. Doppler ultrasonography was used to diagnose DVT. Patients were divided into the 0-2d group, 3-4d group, 5-7d group, and >7d group according to TFITS. The correlation between TFITS and preoperative DVT was assessed using logistic regression according to the adjusted model. Result A total of 2831 patients were included in the study. The mean（+/-SD） TFITS was 6.11 ± 3.76 (0 to 21 d). A total of 821 (29.0%) cases had preoperative DVT, with the incidence of DVT being 8.0% in the 0-2d group, 23.8% in the 3-4d group, 32.0% in the 5-7d group, and 36.2% in the >7d group, with statistically significant differences(P＜0.05) among all the groups. The incidence of preoperative DVT increased with prolonged preoperative time. In the fully adjusted model, TFITS was positively correlated with the incidence of preoperative DVT (OR: 1.093; 95% CI: 1.068-1.118; P = 0.000), and the strength of the association increased with increasing time. Conclusion TFITS was an independent risk factor on the incidence of preoperative DVT. After excluding the effect of other factors, each 1d increases in TFITS was correlated with a 9.3% increase in the risk of preoperative DVT. The TFITS should be decreased to reduce the risk of preoperative DVT.