A case of rhinocerebral mucormycosis with brain abscess drained by endoscopic endonasal skull base surgery

A 70-year-old Japanese man undergoing remission induction therapy for acute monocytic leukemia (AML-M5b) developed fever and headache, and was started on antibiotics and liposomal amphotericin B (L-AMB). There was no improvement, and computed tomography and contrast-enhanced magnetic resonance imagi...

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Bibliographic Details
Published inMedical mycology case reports Vol. 30; pp. 22 - 25
Main Authors Uraguchi, Kensuke, Kozakura, Kenichi, Oka, Satoshi, Higaki, Takaya, Makihara, Seiichiro, Imai, Toshi, Doi, Akira, Ohta, Tsuyoshi, Kariya, Shin, Nishizaki, Kazunori
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.12.2020
Elsevier
Subjects
Acute monocytic leukemia
Acute rhinosinusitis
Brain abscess
Case Report
Endoscopic endonasal skull base surgery
Rhinocerebral mucormycosis
Brain abscess
Acute monocytic leukemia
Rhinocerebral mucormycosis
Acute rhinosinusitis
Endoscopic endonasal skull base surgery
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Summary:A 70-year-old Japanese man undergoing remission induction therapy for acute monocytic leukemia (AML-M5b) developed fever and headache, and was started on antibiotics and liposomal amphotericin B (L-AMB). There was no improvement, and computed tomography and contrast-enhanced magnetic resonance imaging revealed acute rhinosinusitis and brain abscess. Successful endoscopic endonasal surgery was performed at this point, providing drainage for the rhinosinusitis and abscess. Histopathological findings showed the mucormycosis.
ISSN:2211-7539
2211-7539
DOI:10.1016/j.mmcr.2020.09.004