Radiation-Chemical Biotechnology for Producing Ultrashort (50-100n) Single-Chain Polydeoxyribonucleotides with Anticancer Activity

The fundamental possibility of obtaining ultrashort (50n-100n) single-stranded polydeoxyribonucleotides by the method of radiation-chemical destruction of total yeast DNA was established and their anticancer activity was shown.

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Bibliographic Details
Published inBulletin of experimental biology and medicine Vol. 171; no. 1; pp. 74 - 76
Main Authors Stovbun, S. V., Vedenkin, A. S., Mikhaleva, M. G., Bukhvostov, A. A., Kuznetsov, D. A.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.05.2021
Springer
Springer Nature B.V
Subjects
Antitumor activity
Biomedical and Life Sciences
Biomedicine
Biotechnologies
Biotechnology
Cancer
Care and treatment
Cell Biology
DNA
Enzymes
Internal Medicine
Laboratory Medicine
Nucleic acids
Pathology
Polydeoxyribonucleotides
Radiation
polydeoxyribonucleotides
radiation-chemical destruction
MTT test
DNA
cytotoxicity
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Summary:The fundamental possibility of obtaining ultrashort (50n-100n) single-stranded polydeoxyribonucleotides by the method of radiation-chemical destruction of total yeast DNA was established and their anticancer activity was shown.
Bibliography:ObjectType-Article-1
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ObjectType-Feature-2
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ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-021-05175-7