A case of small cell carcinoma of the vagina

Primary small cell carcinoma of the vagina is quite rare, and a standard treatment has not been established yet. Herein, we report a case of an 81-year-old woman who was diagnosed with a vaginal tumor without continuity with the uterine cervix. Histopathological diagnosis indicated alveolar solid gr...

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Bibliographic Details
Published inRare tumors Vol. 5; no. 4; pp. e58 - 191
Main Authors Tamura, Ryosuke, Yokoyama, Yoshihito, Kobayashi, Asami, Osawa, Yuuki, Shigeto, Tatsuhiko, Futagami, Masayuki, Mizunuma, Hideki
Format Journal Article
LanguageEnglish
Published England PAGEPress Publications 05.12.2013
PAGEPress Publications, Pavia, Italy
SAGE Publishing
Subjects
Case Report
small cell carcinoma of the vagina, radiotherapy
small cell carcinoma of the vagina
radiotherapy
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Summary:Primary small cell carcinoma of the vagina is quite rare, and a standard treatment has not been established yet. Herein, we report a case of an 81-year-old woman who was diagnosed with a vaginal tumor without continuity with the uterine cervix. Histopathological diagnosis indicated alveolar solid growth of nuclear chromatin-rich atypical cells with a high N/C ratio and a partially recognized rosette-like structure, suggesting a differentiated neuroendocrine system. Chromogranin A and synaptophysin were positive. Stage I vaginal small cell carcinoma localized to the vagina was diagnosed. The tumor disappeared by radiation monotherapy with external beam irradiation and endocavitary irradiation. The patient remains alive without any disease 1 year and 8 months after the treatment, suggesting the efficacy of radiotherapy in small cell carcinoma of the vagina.
ISSN:2036-3605
2036-3613
2036-3613
DOI:10.4081/rt.2013.e58