N‐back training and transfer effects revealed by behavioral responses and EEG

• Published in: Brain and behavior Vol. 8; no. 11; pp. e01136 - n/a
• Main Authors: Pergher, Valentina, Wittevrongel, Benjamin, Tournoy, Jos, Schoenmakers, Birgitte, Van Hulle, Marc M.
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.11.2018; John Wiley and Sons Inc
• Subjects: Accuracy; Adult; Aged; age‐related differences; Attention - physiology; Cognition - physiology; Electroencephalography; Event-Related Potentials, P300 - physiology; Evoked Potentials - physiology; Female; Healthy Volunteers; Humans; Intelligence - physiology; Male; Memory, Short-Term - physiology; Middle Aged; N‐back task; Older people; Original Research; P300 ERP; Psychotherapy - methods; Reaction Time - physiology; Spatial Memory - physiology; transfer effects; Transfer, Psychology - physiology; working memory training; Young Adult; age-related differences; working memory training; N-back task; transfer effects; P300 ERP
• ISSN: 2162-3279; 2162-3279
• DOI: 10.1002/brb3.1136

Introduction Cognitive function performance decreases in older individuals compared to young adults. To curb this decline, cognitive training is applied, but it is not clear whether it improves only the trained task or also other cognitive functions. To investigate this, we considered an N‐back working memory (WM) training task and verified whether it improves both trained WM and untrained cognitive functions. Methods As EEG studies have noted task difficulty and age‐related changes in time‐locked EEG responses, called event‐related potentials (ERPs), we focused on the relation between the P300 ERP component, task difficulty level, and behavior response accuracy and reaction time (RT) in young and older healthy adults. We used two groups of young and older healthy participants to assess the effect of N‐back training: cognitive training group (CTG) and passive control group (PCG). Before and after training, cognitive tests were administered to both groups to evaluate transfer effects. Results Despite the observed age‐related differences in the P300 ERP component and in terms of RT and accuracy, our findings demonstrate a stronger improvement in the trained task for older CTGs compared to younger CTGs, larger near‐ and far‐transfer effect to WM and fluid intelligence for both younger and older CTGs, and a far‐transfer effect to attention but only for older adults. Significant differences in response accuracy were shown between young and older subjects in spatial memory and attention tests. Conclusion The application of a WM training is a promising tool for both healthy adults, and in particular for older subjects, as it showed physiological and behavioral differences in cognitive plasticity across life span and evidence of benefits in the trained task and near‐/far‐transfer effects to other cognitive functions. Cognitive functions decrease with age. Cognitive training improves performance in the trained task and also other cognitive functions. Differences in the P300 ERP component and behavioral responses are shown between young and older healthy adults.