Open Data Revolution in Clinical Research: Opportunities and Challenges

Efforts for sharing individual clinical data are gaining momentum due to a heightened recognition that integrated data sets can catalyze biomedical discoveries and drug development. Among the benefits are the fact that data sharing can help generate and investigate new research hypothesis beyond tho...

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Published inClinical and translational science Vol. 13; no. 4; pp. 665 - 674
Main Authors Shahin, Mohamed H., Bhattacharya, Sanchita, Silva, Diego, Kim, Sarah, Burton, Jackson, Podichetty, Jagdeep, Romero, Klaus, Conrado, Daniela J.
Format Journal Article
LanguageEnglish
Published United States John Wiley & Sons, Inc 01.07.2020
John Wiley and Sons Inc
Wiley
Subjects
Alzheimer's disease
Biomarkers
Cancer
Clinical trials
Consortia
Drug development
Drug therapy
Information sharing
Initiatives
Lifestyles
Longitudinal studies
Medical research
Modernization
Oncology
Researchers
Review
Reviews
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Summary:Efforts for sharing individual clinical data are gaining momentum due to a heightened recognition that integrated data sets can catalyze biomedical discoveries and drug development. Among the benefits are the fact that data sharing can help generate and investigate new research hypothesis beyond those explored in the original study. Despite several accomplishments establishing public systems and guidance for data sharing in clinical trials, this practice is not the norm. Among the reasons are ethical challenges, such as privacy of individuals, data ownership, and control. This paper creates awareness of the potential benefits and challenges of sharing individual clinical data, how to overcome these challenges, and how as a clinical pharmacology community we can shape future directions in this field.
Bibliography:ObjectType-Article-2
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ISSN:1752-8054
1752-8062
DOI:10.1111/cts.12756