A rare case of multiple myeloma with intracranial extramedullary relapse: One or more myeloma clones?

• Published in: Clinical case reports Vol. 7; no. 9; pp. 1629 - 1636
• Main Authors: Markovic, Uros, Calafiore, Valeria, Martino, Enrica, Giubbolini, Rachele, Parisi, Marina Silvia, Romano, Alessandra, Del Fabro, Vittorio, Di Raimondo, Francesco, Conticello, Concetta
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.09.2019; John Wiley and Sons Inc; Wiley
• Subjects: Anemia; Biopsy; Bone marrow; bortezomib; Case Report; Case Reports; extramedullary disease; Family medical history; Laboratories; Medical prognosis; Multiple myeloma; NMR; Nuclear magnetic resonance; Patients; refractoriness; Stem cells; Targeted cancer therapy; Urine; multiple myeloma; bortezomib; refractoriness; extramedullary disease
• ISSN: 2050-0904; 2050-0904
• DOI: 10.1002/ccr3.2292

In a minority of relapsed myeloma, patient's disease may spread into extramedullary sites, associated with high degrees of heterogeneity. The breadth of myeloma therapeutic armamentarium allows clinicians to manage its heterogeneous presentation, including intracranial relapses, with fair success resulting in a significant prolongation of survival. In a minority of relapsed myeloma, patient's disease may spread into extramedullary sites, associated with high degrees of heterogeneity. The breadth of myeloma therapeutic armamentarium allows clinicians to manage its heterogeneous presentation, including intracranial relapses, with fair success resulting in a significant prolongation of survival.