European Headache Federation guideline on idiopathic intracranial hypertension

• Published in: Journal of headache and pain Vol. 19; no. 1; pp. 93 - 15
• Main Authors: Hoffmann, Jan, Mollan, Susan P, Paemeleire, Koen, Lampl, Christian, Jensen, Rigmor H, Sinclair, Alexandra J
• Format: Journal Article
• Language: English
• Published: Milan Springer Milan 08.10.2018; BMC
• Subjects: Consensus; Consensus Article; Headache - etiology; Headache - therapy; Humans; Internal Medicine; Medicine; Medicine & Public Health; Neurology; Pain Medicine; Pseudotumor Cerebri - etiology; Pseudotumor Cerebri - therapy; Randomized Controlled Trials as Topic; Idiopathic Intracranial Hypertension; European Headache Federation; Evidence-based Treatment Strategies; Bilateral Sixth Nerve Palsy; Optic Nerve Sheath Fenestration (ONSF)
• ISSN: 1129-2369; 1129-2377; 1129-2377
• DOI: 10.1186/s10194-018-0919-2

Background Idiopathic Intracranial Hypertension (IIH) is characterized by an elevation of intracranial pressure (ICP no identifiable cause. The aetiology remains largely unknown, however observations made in a number of recent clinical studies are increasing the understanding of the disease and now provide the basis for evidence-based treatment strategies. Methods The Embase, CDSR, CENTRAL, DARE and MEDLINE databases were searched up to 1st June 2018. We analyzed randomized controlled trials and systematic reviews that investigate IIH. Results Diagnostic uncertainty, headache morbidity and visual loss are among the highest concerns of clinicians and patients in this disease area. Research in this field is infrequent due to the rarity of the disease and the lack of understanding of the underlying pathology. Conclusions This European Headache Federation consensus paper provides evidence-based recommendations and practical advice on the investigation and management of IIH.