Red cell distribution width to albumin ratio is a risk factor for atrial fibrillation in subjects hospitalized with coronary angiography

• Published in: BMC cardiovascular disorders Vol. 24; no. 1; pp. 95 - 8
• Main Authors: Li, Wenhua, Song, Yanbin
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 08.02.2024; BioMed Central; BMC
• Subjects: Albumin; Analysis; Angiography; Atrial fibrillation; Atrial Fibrillation - diagnosis; Atrial Fibrillation - etiology; Blood pressure; Body mass index; Cardiac arrhythmia; Cardiovascular disease; Cardiovascular diseases; Cholesterol; Confounding (Statistics); Coronary Angiography - adverse effects; Diabetes; EKG; Electrocardiography; Erythrocyte Indices; Erythrocytes; Fibrillation; Health aspects; Heart attacks; Heart failure; High density lipoprotein; Humans; Hypertension; Inflammation; Measurement; Medical examination; Medical imaging; Mortality; Neutrophils; Prevention; Red cell distribution width; Regression analysis; Retrospective Studies; Risk Factors; Statistical analysis; Stroke; China; Albumin; Red cell distribution width; Atrial fibrillation
• ISSN: 1471-2261; 1471-2261
• DOI: 10.1186/s12872-024-03772-8

Red cell distribution width to albumin ratio (RAR) has been demonstrated to be associated with the risk of cardiovascular diseases. However, it is still unknown whether the RAR affects atrial fibrillation (AF). Therefore, this study aimed to investigate the association between RAR and AF in subjects hospitalized with coronary angiography. A total of 2436 participants were retrospectively included. Red cell distribution width, albumin and other data were collected. AF was confirmed using 12-lead electrocardiogram (ECG) or 24-h Holter. All participants were divided into four groups according to the RAR values by quartile (Q1, Q2, Q3, Q4). Univariate and multivariate logistic regression were performed to examine the correlation between RAR and AF. Among the 2436 participants, 227 (9.3%) AF cases were observed. The RDW and RAR were significantly higher in AF group than in non-AF group (all P < 0.001). Univariate logistic regression showed an positive association between RAR and AF (P < 0.001). In multivariate logistic regression, RAR was found to be an independent risk factor of AF after adjusting for confounding factors (OR:2.015, 95%CI:1.315-3.089, P = 0.001). The present study indicated that elevated RAR level was independently correlated with increased risk of AF in subjects hospitalized with coronary angiography.