Clinical application of calcium silicate-based bioceramics in endodontics

Pulp treatment is extremely common in endodontics, with the main purpose of eliminating clinical symptoms and preserving tooth physiological function. However, the effect of dental pulp treatment is closely related to the methods and materials used in the process of treatment. Plenty of studies abou...

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Published inJournal of translational medicine Vol. 21; no. 1; p. 853
Main Authors Wang, Xinyuan, Xiao, Yizhi, Song, Wencheng, Ye, Lanxiang, Yang, Chen, Xing, Yuzhen, Yuan, Zhenglin
Format Journal Article
LanguageEnglish
Published England BioMed Central Ltd 25.11.2023
BioMed Central
BMC
Subjects
Bioactivity
Bioceramics
Biocompatibility
Biological activity
Calcium
Calcium Compounds - pharmacology
Calcium Compounds - therapeutic use
Calcium silicate
Care and treatment
Clinical outcomes
Clinical trials
Dental pulp
Dentin
Dentistry
Drug Combinations
Endodontics
Gum disease
Humans
Mechanical properties
Oral health
Oxides - pharmacology
Oxides - therapeutic use
Root Canal Filling Materials - pharmacology
Root Canal Filling Materials - therapeutic use
Root canals
Teeth
Therapeutic applications
Tissue engineering
China
Bioceramics
Biocompatibility
Bioactivity
Endodontics
Calcium silicate
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Summary:Pulp treatment is extremely common in endodontics, with the main purpose of eliminating clinical symptoms and preserving tooth physiological function. However, the effect of dental pulp treatment is closely related to the methods and materials used in the process of treatment. Plenty of studies about calcium silicate-based bioceramics which are widely applied in various endodontic operations have been reported because of their significant biocompatibility and bioactivity. Although most of these materials have superior physical and chemical properties, the differences between them can also have an impact on the success rate of different clinical practices. Therefore, this review is focused on the applications of several common calcium silicate-based bioceramics, including Mineral trioxide aggregate (MTA), Biodentine, Bioaggregate, iRoot BP Plus in usual endodontic treatment, such as dental pulp capping, root perforation repair, regenerative endodontic procedures (REPs), apexification, root-end filling and root canal treatment (RCT). Besides, the efficacy of these bioceramics mentioned above in human trials is also compared, which aims to provide clinical guidance for their clinical application in endodontics.
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ISSN:1479-5876
1479-5876
DOI:10.1186/s12967-023-04550-4