The effect of a multidisciplinary care clinic on the outcomes in pediatric chronic kidney disease

• Published in: Pediatric nephrology (Berlin, West) Vol. 27; no. 10; pp. 1921 - 1927
• Main Authors: Ajarmeh, Salma, Er, Lee, Brin, Genevieve, Djurdjev, Ognjenka, Dionne, Janis M.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.10.2012; Springer; Springer Nature B.V
• Subjects: Adolescent; Ambulatory Care Facilities - economics; Ambulatory Care Facilities - organization & administration; Ambulatory Care Facilities - standards; Analysis; Anemia; Anemia - epidemiology; Anemia - therapy; Biomarkers - blood; Blood Pressure; Bone Diseases, Metabolic - epidemiology; Bone Diseases, Metabolic - therapy; British Columbia - epidemiology; Chi-Square Distribution; Child; Children; Chronic kidney failure; Clinical outcomes; Comorbidity; Cost Savings; Creatinine; Cross-Sectional Studies; Disease Progression; Diseases; Evidence-based medicine; Female; Glomerular Filtration Rate; Growth Disorders - epidemiology; Growth Disorders - therapy; Health Care Costs; Hemodialysis; Hemoglobin; Hospitalization; Hospitals; Humans; Hypertension - epidemiology; Hypertension - therapy; Interdisciplinary Communication; Kidney - physiopathology; Kidney diseases; Linear Models; Logistic Models; Male; Medicine; Medicine & Public Health; Metabolism; Nephrology; Nutrition; Nutritional Status; Organizational Objectives; Original Article; Patient Care Team - organization & administration; Patient Care Team - standards; Patient outcomes; Patients; Pediatrics; Prevalence; Renal Insufficiency, Chronic - blood; Renal Insufficiency, Chronic - diagnosis; Renal Insufficiency, Chronic - economics; Renal Insufficiency, Chronic - epidemiology; Renal Insufficiency, Chronic - physiopathology; Renal Insufficiency, Chronic - therapy; Renal replacement therapy; Retrospective Studies; Severity of Illness Index; Social workers; Standard of Care - economics; Time Factors; Treatment Outcome; Urology; British Columbia; Canada; British Columbia Canada; Growth and nutrition; Bone mineral metabolism; Blood pressure; Hospitalization; Anemia; Disease progression
• ISSN: 0931-041X; 1432-198X
• DOI: 10.1007/s00467-012-2209-6

Background Current best evidence-based practice for children with chronic kidney disease (CKD) attempts to achieve good clinical outcomes through careful management of comorbidities and is likely best achieved with a multidisciplinary care (MDC) CKD clinic. Methods In this retrospective study of children with CKD in British Columbia, Canada, we analyzed clinical outcomes in a cohort of 73 CKD patients from 2003 under a standard care model and a second cohort of 125 CKD patients from 2009 under a MDC clinic model. Results Patient demographics were similar, but there was a decrease in the percentage of patients with CKD stage 3–5 in 2009 (59 vs. 75 %; p = 0.002), although the absolute number increased. After adjustment for severity of CKD, hemoglobin was significantly higher (13.0 g/dl vs. 12.2 g/dl, p  < 0.03), calcium was significantly higher (9.6 mg/dl vs. 9.1 mg/dl, p  < 0.001), and albumin was significantly higher (4.4 g/dl vs. 3.8 g/dl, p < 0.001) in the 2009 MDC cohort. The rate of disease progression, assessed by annualized estimated glomerular filtration rate (eGFR) slope, improved from –4.0 ml/min/1.73 m 2 in the 2003 cohort to 0.5 ml/min/1.73 m 2 in the 2009 cohort (p < 0.01). Blood pressure control was better in 2009 although not statistically significant. Conclusions Multidisciplinary care improved the outcomes of children with CKD especially in anemia management, bone mineral metabolism, nutrition, and renal disease progression.