Lower dental caries prevalence associated to chronic kidney disease: a systematic review

• Published in: Pediatric nephrology (Berlin, West) Vol. 29; no. 5; pp. 771 - 778
• Main Authors: Andrade, Marcia Rejane Thomas Canabarro, Antunes, Lívia Azeredo Alves, Soares, Rosangela Maria de Araújo, Leão, Anna Theresa Tome, Maia, Luciane Cople, Primo, Laura Guimarães
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.05.2014; Springer; Springer Nature B.V
• Subjects: Adolescent; Causes of; Child; Chronic kidney failure; Complications and side effects; Demographic aspects; Dental caries; Dental Caries - epidemiology; Dentistry; Diagnosis; Humans; Kidney diseases; Medicine; Medicine & Public Health; Nephrology; Observational studies; Oral hygiene; Patients; Pediatrics; Renal Insufficiency, Chronic - complications; Renal Insufficiency, Chronic - epidemiology; Renal replacement therapy; Review; Risk factors; Systematic review; Teenagers; Teeth; Urology; Brazil; Rio de Janeiro Brazil; Dental caries; Chronic renal failure; Children; Adolescents
• ISSN: 0931-041X; 1432-198X
• DOI: 10.1007/s00467-013-2437-4

Background The aim of this systematic review was to determine whether there is any evidence in the literature referring to a lower prevalence of dental caries in children and adolescents with chronic kidney disease (CKD) compared to healthy individuals. Methods A search of the PubMed Medline, Ovid Medline and Cochrane Library databases was performed using the MeSH terms “dental caries” and “chronic renal failure”. To be eligible for entry in our study, controlled observational studies had to present a decayed, missing and filled index for primary teeth (dmft) and/or for permanent teeth (DMFT) in children and adolescents with CKD. Results After evaluation of title, keywords and abstracts of the articles selected, six articles met the inclusion criteria. Three of these six articles included studies which showed susceptibility to bias and possible confounding factors. A subsequent assessment of the six studies revealed that the mean caries indices in both primary (dmf) and permanent (DMF) teeth were lower in the children and adolescents with CKD compared with healthy individuals. Conclusion Data in the literature weakly support a lower prevalence of caries in children and adolescents with CKD than in their healthy counterparts. There is still a lack of well-designed studies that provide better scientific evidence in support of this conclusion.