Urinary Tract Infections and Associated Factors among Patients with Indwelling Urinary Catheters Attending Bugando Medical Centre a Tertiary Hospital in Northwestern Tanzania

• Published in: Microorganisms (Basel) Vol. 10; no. 2; p. 473
• Main Authors: Ndomba, Asteria L M, Laisser, Rose M, Silago, Vitus, Kidenya, Benson R, Mwanga, Joseph, Seni, Jeremiah, Mshana, Stephen E
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 21.02.2022; MDPI
• Subjects: Antibiotics; Bacteria; Bladder; Bugando Medical Centre; Catheterization; Catheters; E coli; Escherichia coli; Generalized linear models; Gram-negative bacteria; Health care facilities; Hospitals; Industrialized nations; indwelling urinary catheterization; Intubation; Klebsiella; Klebsiella species; Laboratories; Medical instruments; Morbidity; Nosocomial infections; Patients; Population; Urinary tract; Urinary tract infections; Urine; Urogenital system; Urology; United Kingdom > UK; Tanzania; indwelling urinary catheterization; Escherichia coli; Bugando Medical Centre; Klebsiella species; urinary tract infections
• ISSN: 2076-2607; 2076-2607
• DOI: 10.3390/microorganisms10020473

Complications of indwelling urinary catheterization (IUC) are associated with significant morbidity and mortality, thus affecting patient's well-being. Understanding the magnitude and factors associated with complications is crucial in designing appropriate preventive strategies. A cross-sectional study was conducted at Bugando Medical Centre, involving patients with long-term and short-term IUC from December 2016 to September 2017. The data were analyzed by STATA 13.0. Catheter-associated urinary tract infection (CA-UTI) was the leading (56.8%; 250/440) complication among patients with IUC. Gram-negative bacteria were predominantly isolated (98.1%, 252/257), whereas (30.7%, 79/257) and spp. (29.6%, 76/257) were the leading pathogens. CA-UTI was significantly higher among out-patients than in-patients (82.2% v 35.3%, < 0.001). Older age (OR: 1.3, (95%CI: 1.1-1.5), < 0.001), level of education (OR: 1.8, (95%CI: 1.1-3.1), = 0.029) and catheter duration of ≥6 weeks (OR: 2.43, (95%CI: 1.1-5.5), = 0.031) independently predicted CA-UTI among outpatients, while female gender (OR: 2.1, (95%CI: 1.2-3.7), = 0.014), catheter bags not freely hanging (OR: 0.4, (95%CI: 0.2-0.7), = 0.002) and residing outside Mwanza region (OR: 0.4, (95%CI: 0.2-0.6), < 0.001) predicted CA-UTI among in-patients. CA-UTI is the common complication among patients with IUC, significantly higher in out-patients than in-patients. We recommend involving patients and carers in infection prevention and control measures in out-patients living with IUC.