Purinergic P2 Receptors: Novel Mediators of Mechanotransduction

• Published in: Frontiers in pharmacology Vol. 12; p. 671809
• Main Authors: Kong, Qihang, Quan, Yue, Tian, Geer, Zhou, Junteng, Liu, Xiaojing
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 07.05.2021
• Subjects: cellular mechanotransduction; mechanical stress; mechanoreceptors; nucleotides; Pharmacology; purinergic P2 receptors

Mechanosensing and mechanotransduction are vital processes in mechanobiology and play critical roles in regulating cellular behavior and fate. There is increasing evidence that purinergic P2 receptors, members of the purinergic family, play a crucial role in cellular mechanotransduction. Thus, infor...