Advances in Nanoparticles for Effective Delivery of RNA Therapeutics

• Published in: Biochip journal Vol. 16; no. 2; pp. 128 - 145
• Main Authors: Byun, Min Ji, Lim, Jaesung, Kim, Se-Na, Park, Dae-Hwan, Kim, Tae-Hyung, Park, Wooram, Park, Chun Gwon
• Format: Journal Article
• Language: English
• Published: Seoul The Korean BioChip Society (KBCS) 01.06.2022; Springer Nature B.V; 한국바이오칩학회
• Subjects: Acids; Atherosclerosis; Biomedical Engineering and Bioengineering; Biotechnology; Brain research; Cancer therapies; Chemistry; Chemistry and Materials Science; Cystic fibrosis; Efficiency; Gene expression; Genomes; Immunogenicity; Infectious diseases; Kinases; Lipids; Melanoma; MicroRNAs; mRNA; mRNA vaccines; Nanoparticles; Nanotechnology; Ovarian cancer; Peptides; Platforms; Polymers; Prostate; Protein expression; Proteins; Review; Review Article; Ribonucleic acid; RNA; Severe acute respiratory syndrome coronavirus 2; siRNA; Toxicity; Tumor necrosis factor-TNF; 생물공학; Nanoparticles; RNA delivery; Gene therapy; Nanomedicine; Biomaterials

RNA therapeutics, including messenger RNA (mRNA) and small interfering RNA (siRNA), are genetic materials that mediate the translation of genetic direction from genes to induce or inhibit specific protein production. Although the interest in RNA therapeutics is rising globally, the absence of an eff...