First enantioseparation and circular dichroism spectra of Au38 clusters protected by achiral ligands

• Published in: Nature communications Vol. 3; no. 1; p. 798
• Main Authors: Dolamic, Igor, Knoppe, Stefan, Dass, Amala, Bürgi, Thomas
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 24.04.2012; Nature Publishing Group; Nature Pub. Group
• Subjects: 639/638/11; 639/638/403/935; 639/638/440; Humanities and Social Sciences; multidisciplinary; Science; Science (multidisciplinary)
• ISSN: 2041-1723; 2041-1723
• DOI: 10.1038/ncomms1802

Bestowing chirality to metals is central in fields such as heterogeneous catalysis and modern optics. Although the bulk phase of metals is symmetric, their surfaces can become chiral through adsorption of molecules. Interestingly, even achiral molecules can lead to locally chiral, though globally racemic, surfaces. A similar situation can be obtained for metal particles or clusters. Here we report the first separation of the enantiomers of a gold cluster protected by achiral thiolates, Au 38 (SCH 2 CH 2 Ph) 24 , achieved by chiral high-performance liquid chromatography. The chirality of the nanocluster arises from the chiral arrangement of the thiolates on its surface, forming 'staple motifs'. The enantiomers show mirror-image circular dichroism responses and large anisotropy factors of up to 4×10 −3 . Comparison with reported circular dichroism spectra of other Au 38 clusters reveals that the influence of the ligand on the chiroptical properties is minor. Clusters of gold atoms protected with achiral thiolates can display chirality, and such chiral nanoparticles could open new possibilities in catalysis and sensing. Here, the first separation of the enantiomers of a gold cluster, protected by achiral thiolates, Au 38 (SCH 2 CH 2 Ph) 24 , is achieved.