The Prevalence of Drug-Resistant Streptococcus pneumoniae In Atlanta

• Published in: The New England journal of medicine Vol. 333; no. 8; pp. 481 - 486
• Main Authors: Hofmann, Jo, Cetron, Martin S, Farley, Monica M, Baughman, Wendy S, Facklam, Richard R, Elliott, John A, Deaver, Katherine A, Breiman, Robert F
• Format: Journal Article
• Language: English
• Published: Boston, MA Massachusetts Medical Society 24.08.1995
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Antibacterial agents; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antimicrobial agents; Biological and medical sciences; Cefotaxime; Child; Child, Preschool; Children; Disease control; Drug resistance; Drug Resistance, Microbial; Ear diseases; Erythromycin; Female; Georgia - epidemiology; Humans; Incidence; Infant; Infant, Newborn; Laboratories; Male; Medical sciences; Middle Aged; Mortality; Penicillin; Pharmacology. Drug treatments; Pneumococcal Infections - epidemiology; Pneumococcal Infections - microbiology; Pneumonia; Population Surveillance; Prevalence; Serotyping; Strains (organisms); Streptococcus infections; Streptococcus pneumoniae; Streptococcus pneumoniae - classification; Streptococcus pneumoniae - drug effects; Streptococcus pneumoniae - isolation & purification; Sulfamethoxazole; Trimethoprim; Trimethoprim-sulfamethoxazole; Vaccines; Georgia; Atlanta Georgia; United States > US; Human; Measurement; Prevalence; Streptococcus pneumoniae; Resistance; Streptococcaceae; Antibiotic; Chemotherapy; Treatment; Bacteria; Micrococcales; Adult; Child
• ISSN: 0028-4793; 1533-4406
• DOI: 10.1056/NEJM199508243330803

S treptococcus pneumoniae is a major cause of morbidity and mortality and results in expenditures of over $4 billion yearly in the United States for the treatment of pneumonia, meningitis, bacteremia, sinusitis, and otitis media. 1 – 3 The emergence of drug-resistant S. pneumoniae will make these common infections more difficult to treat. 4 – 6 Most reports regarding drug-resistant pneumococcus in the United States have focused on infections in children, in which the spread of drug-resistant organisms has been linked to day-care centers and the indiscriminate use of antibiotics. 7 – 11 To characterize the epidemiology of drug-resistant S. pneumoniae, we conducted population-based surveillance for . . .