Effect of calcium citrate on bone integration in a rabbit femur defect model

• Published in: Asian Pacific journal of tropical medicine Vol. 5; no. 4; pp. 310 - 314
• Main Authors: Zhang, Wei, Wang, Wei, Chen, Qing-Yu, Lin, Zhong-Qin, Cheng, Shao-Wen, Kou, Dong-Quan, Ying, Xiao-Zhou, Shen, Yue, Cheng, Xiao-Jie, Nie, Peng-Fei, Li, Xiu-Cui, Rompis, Ferdinand An, Huang, Hang, Zhang, Hua, Mu, Zhong-Lin, Peng, Lei
• Format: Journal Article
• Language: English
• Published: India Elsevier B.V 01.04.2012; Department of 0rthopaedic Surgery, the Second Affiliated Hospital of Wenzhou Medical College,109 Xue Yuan Xi Road, Wenzhou 325000, China%Department of 0rthopaedic Surgery, Hospital of Integrated Traditional Chinese and Western Medicine of Wenzhou, Wenzhou, China%Department of Respiratory Medicine, Yuying Children's Hospital Affiliated to Wenzhou Medical College, Wenzhou, Zhejiang, China%Trauma Center of the Affiliated Hospital of Hainan Medical College, 31 Long Hua Road, Haikou, China%Haikou120 Emergency Center, 43 Renmin Da Dao, Haikou 570208, Hainan Province, China%International Nursing School of Hainan Medical College, 3 Xueyuan Road, Haikou 571199, Hainan Province, China%Graduate Department of Hainan Medical College, 3 Xueyuan Road, Haikou 571199, Hainan Province, China%The Second Affiliated Hospital of Wenzhou Medical College, Trauma Center of the Affiliated Hospital of Hainan Medical College, 109 Xue Yuan Xi Road, Wenzhou 325000, China
• Subjects: Animals; Bone; Bone Density Conservation Agents - pharmacology; Bone Regeneration - drug effects; Calcium; Calcium citrate; Calcium Citrate - pharmacology; citrate; Experiment; Femur - diagnostic imaging; Femur - drug effects; Fracture; Fracture healing; healing; Male; Rabbits; Radiography; Random Allocation; Wound Healing - drug effects; Japan; INW, Japan; Fracture healing; Bone; Experiment; Calcium citrate

<正>Objective:To explore effect of calcium citrate on bone integration in a rabbit femur defect model, and to compare the bone formation with different sizes by radiological and histological study. Methods:Twenty-four male Japanese white rabbits were randomly divided into three groups (...