Uterine artery Doppler velocimetry in hypertensive disorder of pregnancy in Nigeria

• Published in: Journal of ultrasonography Vol. 17; no. 71; pp. 253 - 258
• Main Authors: Abidoye, Ibukun A., Ayoola, Oluwagbemiga O., Idowu, Bukunmi M., Aderibigbe, Adeniyi S., Loto, Olabisi M.
• Format: Journal Article
• Language: English
• Published: Poland Sciendo 01.12.2017; Exeley Inc; Medical Communications Sp. z o.o
• Subjects: Diagnosis; Doppler sonography; Doppler ultrasonography; Gestational hypertension; hypertensive disorder of pregnancy; intrauterine growth restriction; Measurement; Medical examination; Original Paper; Patient outcomes; Pregnant women; Risk factors; uterine artery; Uterine circulation; Nigeria; intrauterine growth restriction; Doppler sonography; uterine artery; hypertensive disorder of pregnancy
• ISSN: 2084-8404; 2451-070X
• DOI: 10.15557/jou.2017.0037

To evaluate the value of uterine artery Doppler indices and waveform pattern in predicting fetuses at risk for intrauterine growth restriction in hypertensive disorders of pregnancy. This was a prospective cross-sectional study including 80 pregnant subjects with hypertensive disorders of pregnancy and two control groups. Uterine artery Doppler sonography was performed in all study participants. Uterine artery Doppler indices across the groups were compared using the analysis of variance (ANOVA) while the presence of prediastolic notch was analyzed with the Chi Square test. For the hypertensive disorders of pregnancy group, resistivity index > 0.66 had a sensitivity of 50.0%, specificity of 69.1% and a positive predictive value of 22.2% for predicting intrauterine growth restriction. The odds ratio was 2.2 with a 95% confidence interval of 0.6-7.8. The presence of prediastolic notching had a sensitivity of 100.0%, specificity of 96.0% and a positive predictive value of 80.0% for predicting intrauterine growth restriction. The odds ratio was 22.7 with a 95% confidence interval of 7.5-68.5. Uterine artery Doppler sonography is useful for predicting fetuses at risk for intrauterine growth restriction in hypertensive disorder of pregnancy. Prediastolic notching is more sensitive and more specific than uterine artery resistivity index in predicting fetuses at risk of intrauterine growth restriction in established hypertensive disorder of pregnancy.