Epidemiology of pneumococcal meningitis hospitalizations in pediatric population in Spain (1998–2006)

• Published in: Vaccine Vol. 27; no. 20; pp. 2669 - 2673
• Main Authors: Gil Prieto, R, San Román Montero, J, Gómez Alejandre, C, Alvaro Meca, L.A, Rivero, A, Gil de Miguel, A
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ltd 05.05.2009; Elsevier; Elsevier Limited
• Subjects: Adolescent; Age Factors; Allergy and Immunology; Applied microbiology; Bacteriology; Biological and medical sciences; Child; Child, Preschool; Epidemiology; Fatalities; Female; Fundamental and applied biological sciences. Psychology; Hospitalization; Hospitalization - statistics & numerical data; Humans; Immunization; Incidence; Infant; Infant, Newborn; Information systems; Male; Meningitis; Meningitis, Pneumococcal - epidemiology; Meningitis, Pneumococcal - mortality; Microbiology; Miscellaneous; Mortality; Older people; Pneumococcal; Spain; Spain - epidemiology; Streptococcus pneumoniae; Vaccines; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects); Europe; Spain; Pneumococcal; Meningitis; Hospitalization; Mortality; Spain; Streptococcaceae; Nervous system diseases; Central nervous system disease; Bacteria; Micrococcales; Epidemiology; Streptococcus pneumoniae
• ISSN: 0264-410X; 1873-2518
• DOI: 10.1016/j.vaccine.2009.02.063

Abstract The burden of hospital admissions for pneumococcal meningitis in pediatric population in Spain during a 9-year period was estimated. Data were obtained from the national information system (computerized hospital discharge data). There were 770 hospital admissions with an annual incidence of 1.44 cases per 100,000 population. Rate of death and case-fatality rate were 0.11 per 100,000 population and 7.92%, respectively. The higher incidence and rate of death was found in children up to 12 months of age and the higher case-fatality rate in children of 10–14 years of age. Further studies assessing the incidence of pneumococcal meningitis in post-vaccination period are needed.