The Inducible Nitric Oxide Synthase Locus Confers Protection against Aerogenic Challenge of Both Clinical and Laboratory Strains of Mycobacterium tuberculosis in Mice

• Published in: Infection and Immunity Vol. 69; no. 12; pp. 7711 - 7717
• Main Authors: SCANGA, Charles A, MOHAN, Vellore P, TANAKA, Kathryn, ALLAND, David, FLYNN, Joanne L, CHAN, John
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.12.2001
• Subjects: Aerosols; Animals; Bacterial diseases; Bacterial Infections; Bacteriology; Biological and medical sciences; Bone Marrow Cells - immunology; Experimental bacterial diseases and models; Fundamental and applied biological sciences. Psychology; Genetics; Humans; Immunity, Innate; Infectious diseases; Injections, Intravenous; Macrophages - immunology; Medical sciences; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microbiology; Mycobacterium tuberculosis; Mycobacterium tuberculosis - growth & development; Nitric Oxide Synthase - metabolism; Nitric Oxide Synthase Type II; NOS2 gene; reactive nitrogen intermediates; Reactive Nitrogen Species - metabolism; Species Specificity; Tuberculosis - immunology; Tuberculosis - mortality; Molecular form; Mycobacterial infection; Production function; Synthase; Bacillaceae; Bacillales; Bacillus; Bacteria; Locus; Protection; Enzyme; Rodentia; Nitric-oxide synthase; Strain; Infection; Clinic; Vertebrata; Mammalia; Reactivity; Tuberculosis; Mycobacterium tuberculosis; Mouse; Mycobacteriales; Nitric oxide; Bacteriosis; Mycobacteriaceae; Actinomycetes; Oxidoreductases; Macrophage
• ISSN: 0019-9567; 1098-5522
• DOI: 10.1128/IAI.69.12.7711-7717.2001

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