Lycopene: A Potent Antioxidant with Multiple Health Benefits

• Published in: Journal of nutrition and metabolism Vol. 2024; no. 1; p. 6252426
• Main Authors: Shafe, Mercy Omoye, Gumede, Nontobeko Myllet, Nyakudya, Trevor Tapiwa, Chivandi, Eliton
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 08.06.2024; Hindawi; Wiley
• Subjects: Antioxidants; Apoptosis; Bioavailability; Body fat; Carbon; Carotenoids; Cell cycle; Clinical trials; Cross-sectional studies; Development and progression; Diabetes; Diabetes mellitus; Diet; Dietary supplements; Fatty acids; Food products; Fruits; Hydrocarbons; Insulin; Kinases; Liver; Lycopene; Metabolic disorders; Nervous system; Ovaries; Oxidative stress; Physical properties; Prostate; Review; Tomatoes; Toxicity; Type 2 diabetes
• ISSN: 2090-0724; 2090-0732
• DOI: 10.1155/2024/6252426

Lycopene is a naturally occurring carotenoid predominantly found in tomatoes and tomato‐based products. Like other phytochemicals, it exhibits health beneficial biological activities that can be exploited when it is used as a dietary supplement. In vitro and in vivo , lycopene has been demonstrated to mitigate oxidative stress‐induced metabolic dysfunctions and diseases including inflammation, obesity, and diabetes mellitus. Lycopene has been shown to alleviate metabolic diseases that affect the bone, eye, kidney, liver, lungs, heart, and nervous system. This review presents the state of the art regarding lycopene’s health benefits and its potential applications in health system delivery. Furthermore, lycopene’s protective effects against toxins, safety in its use, and possible toxicity are explored.