Viral metagenomics reveals sapoviruses of different genogroups in stool samples from children with acute gastroenteritis in Jiangsu, China

• Published in: Archives of virology Vol. 165; no. 4; pp. 955 - 958
• Main Authors: Li, Wang, Dong, Surong, Xu, Juan, Zhou, Xiaobin, Han, Junling, Xie, Zhaqing, Gong, Qin, Peng, Hailin, Zhou, Chenglin, Lin, Mei
• Format: Journal Article
• Language: English
• Published: Vienna Springer Vienna 01.04.2020; Springer Nature B.V
• Subjects: Age; Biomedical and Life Sciences; Biomedicine; Brief Report; Caliciviridae Infections - virology; Child, Preschool; Children; China; Feces - virology; Female; Gastroenteritis; Gastroenteritis - virology; genome; Genome, Viral; Genomes; Humans; Infant; Infectious Diseases; Male; Medical Microbiology; Metagenomics; Phylogeny; Sapovirus - classification; Sapovirus - genetics; Sapovirus - isolation & purification; Virology; China
• ISSN: 0304-8608; 1432-8798; 1432-8798
• DOI: 10.1007/s00705-020-04549-y

Sapoviruses (SAVs), including several genogroups (GI to GV), are one of the causes of acute gastroenteritis (AGE). In this study, viral metagenomics revealed the presence of sapoviruses of different genogroups in stool from children with AGE. Eight different complete SAV genomes were determined, of which five belonged to GI and the other three belonged to GII, GIV and GV, respectively. Although they were highly similar to published sequences, the GIV and GV were the first complete genome sequences of these SAVs found in China. In a prevalence investigation, 19% of subjects with AGE were positive for SAVs, while none of the control group was positive.