Nucleic acids for the rational design of reaction circuits

Graphical abstract Highlights ► Nucleic acids can be used to build reaction modules modeled after in vivo or in silico computers. ► In vitro circuits built from these modules perform one-shot calculations or show complex dynamics. ► Applications at the interface with biology, or for molecular-scale...

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Bibliographic Details
Published inCurrent opinion in biotechnology Vol. 24; no. 4; pp. 575 - 580
Main Authors Padirac, Adrien, Fujii, Teruo, Rondelez, Yannick
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 01.08.2013
Subjects
Biotechnology
Computer Simulation
Computers, Molecular
Enzymes - chemistry
Internal Medicine
nucleic acids
Nucleic Acids - chemistry
simulation models
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Summary:Graphical abstract Highlights ► Nucleic acids can be used to build reaction modules modeled after in vivo or in silico computers. ► In vitro circuits built from these modules perform one-shot calculations or show complex dynamics. ► Applications at the interface with biology, or for molecular-scale robotics, are burgeoning.
Bibliography:http://dx.doi.org/10.1016/j.copbio.2012.11.011
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ISSN:0958-1669
1879-0429
DOI:10.1016/j.copbio.2012.11.011