Do wheezy infants recovering from bronchiolitis respond to inhaled salbutamol?

Wheezy infants, less than 6 months of age, were given either inhaled salbutamol or saline in a double-blind study. A significant change in maximal flow at functional residual capacity (VmaxFRC) was defined as being greater than twice the coefficient of variation of the baseline measurements. There w...

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Bibliographic Details
Published inPediatric pulmonology Vol. 10; no. 1; p. 36
Main Authors Sly, P D, Lanteri, C J, Raven, J M
Format Journal Article
LanguageEnglish
Published United States 1991
Subjects
Acute Disease
Albuterol - administration & dosage
Albuterol - therapeutic use
Bronchiolitis, Viral - drug therapy
Bronchiolitis, Viral - physiopathology
Double-Blind Method
Functional Residual Capacity - drug effects
Humans
Infant
Nebulizers and Vaporizers
Respiratory Sounds - drug effects
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Summary:Wheezy infants, less than 6 months of age, were given either inhaled salbutamol or saline in a double-blind study. A significant change in maximal flow at functional residual capacity (VmaxFRC) was defined as being greater than twice the coefficient of variation of the baseline measurements. There was no difference in the infants' response to saline or salbutamol. Wheezy infants, less than 6 months of age, do not have an increase in VmaxFRC following a single dose of inhaled salbutamol.
ISSN:8755-6863
DOI:10.1002/ppul.1950100108