Absolute Ethanol Sclerotherapy for Venous Malformations in the Face and Neck

• Published in: Journal of oral and maxillofacial surgery Vol. 68; no. 7; pp. 1622 - 1627
• Main Authors: Su, Lixin, DDS, PhD, Fan, Xindong, MD, Zheng, Lianzhou, MS, Zheng, Jiawei, DDS
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.07.2010; Elsevier
• Subjects: Adolescent; Adult; Angiography, Digital Subtraction; Arteriovenous Malformations - therapy; Biological and medical sciences; Blood and lymphatic vessels; Cardiology. Vascular system; Child; Child, Preschool; Dentistry; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous; Ethanol - administration & dosage; Face; Female; Follow-Up Studies; Humans; Infant; Injections, Intralesional; Male; Maxillofacial Abnormalities - therapy; Medical sciences; Middle Aged; Neck; Otorhinolaryngology. Stomatology; Phlebography; Retreatment; Sclerosing Solutions - administration & dosage; Sclerotherapy - methods; Surgery; Treatment Outcome; Veins - abnormalities; Veins - drug effects; Young Adult; Vascular disease; Treatment; Ethanol; Stomatology; Surgery; Cardiovascular disease; Neck; Face; Congenital disease; Sclerotherapy; Venous disease; Vein malformation
• ISSN: 0278-2391; 1531-5053
• DOI: 10.1016/j.joms.2009.07.094

Purpose The purpose of the present study was to evaluate the outcomes of sclerotherapy using absolute ethanol for venous malformations in the face and neck. Patients and Methods We treated 60 consecutive patients with venous malformations in the face and neck with sclerotherapy with absolute ethanol under the guidance of digital subtraction angiography. Magnetic resonance imaging was used to evaluate the clinical outcomes of sclerotherapy. Complications were also evaluated. Results The duration of follow-up was a mean of 8 months (range, 3 to 22). Of the 60 patients, 22 were treated once and 38 were treated 2 to 18 times (mean 2.6 times/patient). The mean total volume of ethanol in 60 patients was 11.2 mL (range, 0.5 to 230 mL). Of the 60 patients, 56 had complete volume reduction and a marked response after treatment. No severe skin necrosis or permanent nerve damage occurred. Conclusion Percutaneous sclerotherapy with absolute ethanol under the guidance of venography is a safe and effective treatment for venous malformations in the face and neck.