Intermittent Hypoxemia in Preterm Infants

Intermittent hypoxemia (IH) events are common during early postnatal life, particularly in preterm infants. These events have been associated with multiple morbidities, including retinopathy of prematurity, sleep disordered breathing, neurodevelopmental impairment, and mortality. The relationship be...

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Published inClinics in perinatology Vol. 46; no. 3; p. 553
Main Authors Di Fiore, Juliann M, MacFarlane, Peter M, Martin, Richard J
Format Journal Article
LanguageEnglish
Published United States 01.09.2019
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Abstract Intermittent hypoxemia (IH) events are common during early postnatal life, particularly in preterm infants. These events have been associated with multiple morbidities, including retinopathy of prematurity, sleep disordered breathing, neurodevelopmental impairment, and mortality. The relationship between IH and poor outcomes may depend on the patterns (frequency, duration, and timing) of the IH events. Current treatment modalities used in the clinical setting have been only partially successful in reducing the incidence of apnea and accompanying IH, but the risks and benefits of more aggressive interventions should include knowledge of the relationship between IH and morbidity.
AbstractList Intermittent hypoxemia (IH) events are common during early postnatal life, particularly in preterm infants. These events have been associated with multiple morbidities, including retinopathy of prematurity, sleep disordered breathing, neurodevelopmental impairment, and mortality. The relationship between IH and poor outcomes may depend on the patterns (frequency, duration, and timing) of the IH events. Current treatment modalities used in the clinical setting have been only partially successful in reducing the incidence of apnea and accompanying IH, but the risks and benefits of more aggressive interventions should include knowledge of the relationship between IH and morbidity.
Author MacFarlane, Peter M
Martin, Richard J
Di Fiore, Juliann M
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  organization: Division of Neonatology, Case Western Reserve University, Rainbow Babies & Children's Hospital, Suite RBC 3100, Cleveland, OH 44106-6010, USA. Electronic address: jmd3@case.edu
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  surname: Martin
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  organization: Case Western Reserve University, Rainbow Babies & Children's Hospital, 11100 Euclid Avenue, Suite RBC 3100, Cleveland, OH 44106-6010, USA
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Issue 3
Keywords Hypoxia
Intermittent hypoxemia
Retinopathy of prematurity
Pulse oximetry
Outcomes
Neurodevelopmental impairment
Language English
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Snippet Intermittent hypoxemia (IH) events are common during early postnatal life, particularly in preterm infants. These events have been associated with multiple...
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StartPage 553
SubjectTerms Gestational Age
Global Health
Humans
Hypoxia - blood
Hypoxia - etiology
Incidence
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases - blood
Infant, Premature, Diseases - epidemiology
Oximetry
Oxygen - blood
Title Intermittent Hypoxemia in Preterm Infants
URI https://www.ncbi.nlm.nih.gov/pubmed/31345546
Volume 46
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