Intermittent Hypoxemia in Preterm Infants

Intermittent hypoxemia (IH) events are common during early postnatal life, particularly in preterm infants. These events have been associated with multiple morbidities, including retinopathy of prematurity, sleep disordered breathing, neurodevelopmental impairment, and mortality. The relationship be...

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Bibliographic Details
Published inClinics in perinatology Vol. 46; no. 3; p. 553
Main Authors Di Fiore, Juliann M, MacFarlane, Peter M, Martin, Richard J
Format Journal Article
LanguageEnglish
Published United States 01.09.2019
Subjects
Gestational Age
Global Health
Humans
Hypoxia - blood
Hypoxia - etiology
Incidence
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases - blood
Infant, Premature, Diseases - epidemiology
Oximetry
Oxygen - blood
Hypoxia
Intermittent hypoxemia
Retinopathy of prematurity
Pulse oximetry
Outcomes
Neurodevelopmental impairment
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Summary:Intermittent hypoxemia (IH) events are common during early postnatal life, particularly in preterm infants. These events have been associated with multiple morbidities, including retinopathy of prematurity, sleep disordered breathing, neurodevelopmental impairment, and mortality. The relationship between IH and poor outcomes may depend on the patterns (frequency, duration, and timing) of the IH events. Current treatment modalities used in the clinical setting have been only partially successful in reducing the incidence of apnea and accompanying IH, but the risks and benefits of more aggressive interventions should include knowledge of the relationship between IH and morbidity.
ISSN:1557-9840
DOI:10.1016/j.clp.2019.05.006