Prevalence and Intensity of Schistosoma mansoni Infection and Its Associated Risk Factors Among Patients with and without HIV at Chuahit Health Center, Dembia District, Northwest Ethiopia

• Published in: Research and reports in tropical medicine Vol. 12; pp. 25 - 32
• Main Authors: Kahisay, Mulubrhan, Birhanie, Meseret, Derso, Adane
• Format: Journal Article
• Language: English
• Published: New Zealand Dove Medical Press Limited 01.01.2021; Taylor & Francis Ltd; Dove; Dove Medical Press
• Subjects: Acquired immune deficiency syndrome; AIDS; Development and progression; Disease; Disease transmission; ethiopia; Feces; HIV; HIV (Viruses); HIV testing; Human immunodeficiency virus; Infections; intensity; Medical research; Medicine, Experimental; Original Research; Patients; Population; prevalence; Prevalence studies (Epidemiology); Public health; Risk factors; Sample size; Sampling techniques; Schistosoma mansoni; Statistical analysis; Tropical diseases; Viral infections; viral load; Sub-Saharan Africa; Ethiopia; Africa; intensity; Schistosoma mansoni; prevalence; viral load; Ethiopia
• ISSN: 1179-7282; 1179-7282
• DOI: 10.2147/RRTM.S292899

Human Immunodeficiency Virus-1/AIDS and are widely spread in sub-Saharan Africa including Ethiopia and the co-infection is also prevalent, occurs commonly. infection has been suggested to be a risk factor for HIV transmission and progression. This study aims to assess the prevalence and intensity of infection and associated risk factors among individuals with and without human immunodeficiency virus (HIV) at Chuahit Health Center, West Dembia, Northwest Ethiopia. Institutional based cross-sectional study was conducted from March to April 2019. Two hundred sixty-six study subjects were included in the study by using a systemic and convenient sampling technique. Pretested structured questionnaire was employed to collect data. Single stool samples were collected and examined for eggs. Finger prick and venous blood samples were collected for HIV-1 screening and viral load count. Data were analyzed using SPSS version 20. Independent -test and one-way ANOVA were used to compare the mean of egg counts with HIV status and viral load counts, respectively. A P-value of less than 0.05 was taken as statistically significant. The overall prevalence and intensity of infection was 41 (15.4%) and 162.24 egg per gram of faeces (EPG), respectively. Prevalence of was higher in seronegative study participants though the difference is statistically insignificant. Higher intensity of infection was observed among seropositive study participants with high viral load counts (>1000 copies/mL). Relatively higher prevalence and intensity of infection were found. Study participants' occupation was identified as potential risk factor to infection. Further studies are needed to know the impact of HIV on the prevalence and intensity of infection in the study area.