Concentrations of PCBs, PCDFs and PCDDs in the blood of Yusho patients and their toxic equivalent contribution

• Published in: Chemosphere (Oxford) Vol. 37; no. 9; pp. 1773 - 1780
• Main Authors: Masuda, Yoshito, Schecter, Arnold, Päpke, Olaf
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Oxford Elsevier Ltd 01.10.1998; Elsevier
• Subjects: Benzofurans - blood; Biological and medical sciences; blood; Environmental Exposure; Environmental pollutants toxicology; Food Contamination; food intake; foodborne illness; General aspects; Half-Life; Humans; Japan; Medical sciences; Oryza - poisoning; Plant Oils - poisoning; polychlorinated biphenyls; Polychlorinated Biphenyls - blood; Polychlorinated Biphenyls - poisoning; polychlorinated dibenzodioxins; Polychlorinated Dibenzodioxins - analogs & derivatives; Polychlorinated Dibenzodioxins - blood; polychlorinated dibenzofurans; residues; rice oil; Toxicology; Japan; Asia; Human; Toxicity; Polychlorobiphenyl; Analog; Blood; Equivalency toxic factor
• ISSN: 0045-6535; 1879-1298
• DOI: 10.1016/S0045-6535(98)00242-2

Yusho blood and control serum were colleced in around 1991 and analyzed for congeners of PCDDs, PCDFs and PCBs. In Yusho blood, TEQ was mainly contributed by 2,3,4,7,8-penta-CDF (77–248 ppt), 1,2,3,4,7,8-hexa-CDF (15–37 ppt) and 2,3,3′,4,4′,5-hexa-CB (16–77 ppt). Total TEQ in Yusho blood (185–441 ppt) was only 3–14 times higher than that of control serum (31–61 ppt). It is notable that the concentrations of 3,3′,4,4′,5-, 2,3,3′,4,4′- and 2,3′,4,4′,5-penta-CBs in Yusho blood were comparable to or lower up to 3–5 times than those in control blood.